research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
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research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research The Force Is Strong with This One: Metabolism Overpowers Stem Cell Fate
Metabolism plays a key role in determining stem cell fate.
research Stat3 Partly Inhibits Cell Proliferation Via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research Epidermal Keratinocytes Initiate Wound Healing and Pro-Inflammatory Immune Responses Following Percutaneous Schistosome Infection
Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
research Therapeutic Potential of Endogenous Stem Cells and Cellular Factors for Scar-Free Skin Regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Efficacy and Safety Evaluations of Topical Proretinal Nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation
Fermented soy protein may help prevent bone loss by affecting bone cell activity.
research Investigation of Follicular and Non-Follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles
Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
research The Etiology and Pathogenesis of Alopecia Areata
The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
research Pharmacological and Phytochemical Updates on Citrullus Colocynthis and Citrullus Lanatus
Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research The Pathogenesis of Alopecia Areata
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research Skin-Derived Stem Cells as a Source of Primordial Germ Cell and Oocyte-Like Cells
Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Experimental Assessment of Regenerative Properties of Platelet-Rich Plasma on Human Skin: A Review
PRP helps skin regeneration but needs standardized testing for consistent results.
research Quercetin and Polycystic Ovary Syndrome
Quercetin may help improve symptoms of polycystic ovary syndrome.
research Novel Potential Therapeutic Targets of Alopecia Areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
research The 3D Bioprinted Scaffolds for Wound Healing
3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
research Gellan Gum-Based Hydrogels Support the Recreation of the Dermal Papilla Microenvironment
Gellan gum hydrogels help recreate the environment needed for hair growth cell function.
research Plumbagin, A Natural Compound With Several Biological Effects And Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
research Preservation of a Specialized Phenotype of Dermal Papilla Cells of a Human Hair Follicle Under Cultivation Conditions
Specific conditions are needed to keep hair follicle cells effective for hair growth.
research Topically Applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release
Applying DMG-Na to the skin increases blood flow and may help with skin conditions.