42 citations
,
December 2014 in “Clinical, cosmetic and investigational dermatology” This review indicates that microneedle bipolar RF and fractional bipolar RF treatments offer significant improvement in acne scarring, with optimal results observed about three months after treatment.
36 citations
,
January 2012 in “Dermatology” This case report describes how discontinuing the EGFR inhibitor gefitinib led to rapid improvement of erosive scalp pustules in a woman with non-small-cell lung cancer, despite previous antibiotic and steroid treatment failures.
33 citations
,
October 2005 in “PubMed” In this case study, significant improvement in androgenic alopecia was observed in a 46-year-old woman after 9 months of treatment with dutasteride following limited success with finasteride.
32 citations
,
November 2012 in “Aesthetic Surgery Journal” This article reviews advancements in hair restoration, highlighting improvements in surgical techniques and patient satisfaction, but reports no new clinical results.
31 citations
,
June 2022 in “Journal of Yeungnam Medical Science” This review discusses the use of platelet-rich plasma for musculoskeletal pain relief and function improvement, but notes the current studies' limitations regarding methods and types of treatment.
27 citations
,
March 2011 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that fractional CO(2) laser treatments led to significant improvements in eyelid skin tightening and eyebrow elevation over one year, with no significant side effects reported.
26 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.
26 citations
,
August 2014 in “PubMed” This study found that testosterone treatment in older hypogonadal men caused minor improvements in depressive symptoms and visuospatial memory, but overall, major cognitive benefits were not observed.
24 citations
,
May 2017 in “PubMed” This review evaluates biotin's popularity and its purported benefits for hair improvement but finds no clinical evidence supporting its efficacy.
24 citations
,
September 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This article discusses the combination of mechanical hair removal and medication use for hirsutism improvement, noting that no drugs are approved for this condition in North America, and calls for well-designed comparative studies.
24 citations
,
November 1978 in “JAMA” This study reports that valproic acid is effective in treating absence seizures and shows improvement in other types of seizures, though about 20% of patients experienced adverse effects.
21 citations
,
September 1990 in “Journal of The American Academy of Dermatology” This study reports that six women developed scleroderma while taking L-tryptophan and showed improvement after stopping the supplement and/or starting corticosteroid therapy.
21 citations
,
January 1998 in “Urologia internationalis” This study found that combining dibenyline and finasteride for symptomatic BPH treatment offered modest improvements with fewer additional side effects compared to each drug alone.
16 citations
,
January 2023 in “Molecular Biomedicine” This study demonstrated that customized microneedle arrays can precisely induce targeted hair regeneration and improve hair quality in mice, potentially offering a personalized treatment approach for hair loss.
13 citations
,
June 2011 in “PubMed” This case report describes a man with Touraine-Solente-Golé syndrome who achieved substantial improvement of tufted hair folliculitis after treatment with amoxicillin, clavulanic acid, and topical nadifloxacin.
12 citations
,
January 2013 in “Indian Journal of Dermatology” This case report on a 13-year-old boy with monilethrix observed slight improvement after a two-month trial of oral N-acetyl cysteine, but overall hair density did not improve further.
12 citations
,
September 2012 in “Pediatric Dermatology” This case report describes a 5-year-old boy with extensive epidermal nevus who experienced marked improvement using a topical calcipotriol/betamethasone dipropionate combination ointment.
10 citations
,
September 2014 in “European Journal of Dermatology” This case report describes a 29-year-old woman with longstanding alopecia areata who experienced improvement in her scalp hair loss after 7 years of topical treatment with squaric acid dibutylester.
9 citations
,
September 1947 in “Archives of dermatology and syphilology” This article reviews historical approaches to electrolysis for permanent hair removal and suggests improvements in equipment, but reports no new clinical results.
8 citations
,
September 2011 in “European Journal of Dermatology” This study reports that most cases of frontal fibrosing alopecia did not show significant improvement with available treatments, and effective management remains unproven.
6 citations
,
September 2025 in “Cosmetics” This study introduced laser-assisted exosome delivery and observed early signs of clinical improvement in two patients, though causality cannot be inferred from these preliminary, uncontrolled cases.
5 citations
,
July 2024 in “Aesthetic Surgery Journal” This study found that facial rejuvenation with fat grafting around the prejowl sulcus provided better improvement in jowling and had fewer adverse effects compared to mandibular ligament release without fat grafting.
5 citations
,
January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that PRP was effective for treating alopecia areata with similar improvement across groups, while topical delivery via fractional CO2 laser or microneedling reduced injection pain.
5 citations
,
March 2018 in “Advances in integrative medicine” This case report describes a novel integrative treatment approach leading to symptom improvement and significant reduction of thyroid antibodies in a young woman with Hashimoto’s thyroiditis.
5 citations
,
January 2015 in “Journal of clinical & experimental dermatology research” This study found that the MorrF topical solution combination showed significantly better hair growth improvements than Minoxidil alone in male patients with Androgenetic Alopecia.
5 citations
,
March 2000 in “PubMed” This study found that hair implantation using a biocompatible polyamide fiber resulted in very satisfactory improvements with a low rate of adverse events among 196 patients.
4 citations
,
January 2017 in “Journal of dermatological treatment” This study found that hair transplantation achieved an 86.7% survival rate for cosmetic improvement of alopecia in patients when coup de sabre was no longer active.
4 citations
,
November 2001 in “PubMed” This study observed that 54% of men with male pattern hair loss showed hair growth improvement in the vertex region after 6 months of treatment with oral finasteride.
4 citations
,
July 1992 in “Clinics in Dermatology” Skin surgery has significantly advanced since 1950, with improvements in chemical peels, hair restoration, lasers, and Mohs surgery, and the development of less invasive techniques and specialized training.
3 citations
,
August 2024 in “British Journal of Dermatology” This study observed sustained hair regrowth in some patients with alopecia areata and improvement in vitiligo symptoms, indicating a potential role for dupilumab in treating these conditions, particularly when associated with atopic dermatitis.