Valproic Acid (Depakene)

    November 1978 in “ JAMA ”
    John R. Lewis
    TLDR Valproic acid is effective for various seizures, but may cause temporary side effects like drowsiness and stomach issues.
    Valproic acid was introduced as a new anticonvulsant agent effective in treating absence seizures, tonic-clonic seizures, mixed absence with tonic-clonic seizures, and myoclonic epilepsy. It could be used alone or with other anticonvulsants, potentially allowing for reduced dosages of the latter. Some patients unresponsive to other treatments showed improvement with valproic acid. Adverse reactions occurred in about 20% of patients, with gastrointestinal disturbances and drowsiness being the most common, especially when combined with other anticonvulsants. Hair loss was a less frequent side effect. These adverse effects were generally transient and did not necessitate stopping the medication.
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      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  7 upvotes 4 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Topical VPA - Anyone experiences here?

      in Question  2 upvotes 7 years ago
      The conversation is about using topical valproic acid (VPA) for hair loss, focusing on its application method, usage frequency, and combination with other treatments like micro-needling. No specific experiences with VPA were shared.

      community Here is my hair regrowth plan

      in Treatment  4 upvotes 5 years ago
      The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

      community Figuring out my own experimental protocol

      in Treatment  10 upvotes 2 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

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