January 2015 in “Zurich Open Repository and Archive (University of Zurich)” This study found no significant difference in anagen rate improvement between the CYP-based dietary supplement and placebo in women over 60 with telogen effluvium, possibly due to variable patient inclusion related to hair growth seasonality.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
This study found that patients with alopecia areata showed significant improvement with topical minoxidil, intralesional steroids, and cryotherapy compared to placebo, without interfering side effects.
May 2003 in “Hair transplant forum international” This article presents the author's "Top Ten List" of needed improvements in hair restoration surgery but reports no new clinical results.
This case study reports significant clinical and hormonal improvement in a 21-year-old woman with HAIR-AN syndrome after nine months of treatment with oral contraceptives and spironolactone.
The books were useful but had some areas needing improvement.
May 2026 in “Russian Journal of Skin and Venereal Diseases” This study found that salmon tissue-derived exosomes showed significantly greater improvements in hair density and other parameters compared to platelet-rich plasma in patients with mild to moderate androgenetic alopecia.
November 2025 in “Contribuciones a las Ciencias Sociales” This study reported that a patient with androgenetic alopecia experienced significant improvements in hair density, thickness, and vitality using non-pharmacological approaches such as dietary adjustments, exercise, and supplementary treatments like low-level laser therapy and microneedling, suggesting these may be effective alternative management strategies.
July 2025 in “Dermatology Reports” This review indicates that mesenchymal stem cell therapy may offer clinical improvements for immune-mediated inflammatory skin diseases, showing promise particularly for those unresponsive to traditional treatments, but emphasizes the need for larger, controlled trials to confirm these results.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that collagen peptides consistently provide modest improvements in skin hydration and elasticity and varying benefits for body composition and cardiometabolic markers, although effects on blood sugar control are less consistent; variations in source, dose, and study definitions limit generalizability.
March 2024 in “Poster presentations” This study found that patients with systemic lupus erythematosus reported improvements in symptoms such as fatigue and joint pain after Anifrolumab treatment, with a corresponding decrease in corticosteroid use, although some disease impacts on daily life remained.
January 2024 in “Skin Appendage Disorders” This source reports that SET may offer notable cosmetic improvements and enhance well-being for patients with CA, serving as a cost-effective treatment option either alone or alongside hair transplantation.
May 2021 in “Benha Journal of Applied Sciences” This study found that platelet-rich plasma injections led to significant improvements in atrophic acne scars on the treated side of participants' faces compared to the untreated side.
This study reported that treating PCOS with Karunjchirakam Chooranam showed significant improvements in various cases, suggesting it may be effective for early intervention and prevention of complications.
January 2023 in “International Journal of Trichology” This study found that bicalutamide mesotherapy resulted in subtle hair density improvements and was well tolerated by premenopausal women with androgenetic alopecia.
March 2020 in “QJM: An International Journal of Medicine” In this study, significant improvements in Androgenetic Alopecia were observed with both PRP and SVF therapies, with SVF showing greater effectiveness in increasing terminal and vellus hair counts.
January 2019 in “Dermatologica Sinica” This study observed that dutasteride treatment led to improvement in acne vulgaris among two male patients with androgenetic alopecia, suggesting its potential as a treatment option for concurrent conditions.
152 citations
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October 2010 in “Archives of Dermatology” This study found that daily oral finasteride may increase hair count and improve hair appearance assessments in men with androgenetic alopecia, but it also appears to raise the risk of sexual dysfunction.
108 citations
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March 2006 in “Archives of Dermatology” This study observed that 62% of premenopausal women with female pattern hair loss reported improvement when treated with oral finasteride and an oral contraceptive containing drospirenone and ethinyl estradiol.
108 citations
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December 2003 in “Lasers in surgery and medicine” This study found that combining near-infrared laser phototherapy with indocyanine green application may improve acne vulgaris by reducing active lesions and inflammation without side effects.
80 citations
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August 2002 in “Journal of Dermatology” This study found that combining oral finasteride with topical minoxidil resulted in the greatest improvement in hair growth for male patients with androgenetic alopecia, compared to using any single treatment.
78 citations
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October 2003 in “Cochrane library” This review found that adding cyproterone acetate to estradiol showed a subjective improvement in hirsutism versus placebo, but comparisons with other therapies revealed no clinical differences.
70 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study reports that the TrichoScan method effectively measures hair growth parameters and detected significant improvements in hair counts and thickness in men with androgenetic alopecia after finasteride treatment.
69 citations
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August 2006 in “Behavior Therapy” This study found that group behavior therapy for trichotillomania led to greater short-term symptom improvement compared to supportive therapy, but did not achieve clinically significant changes or prevent relapse over six months.
68 citations
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April 2002 in “Journal of Alternative and Complementary Medicine” This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
65 citations
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April 2002 in “Journal of Alternative and Complementary Medicine” This study found that 60% of men with mild to moderate androgenetic alopecia showed improvement after treatment with botanically derived 5AR inhibitors, suggesting these compounds may be effective, though larger trials are needed.
57 citations
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February 2018 in “Journal of the American Academy of Dermatology” This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.
48 citations
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December 2022 in “Biomolecules” This review discusses recent advancements in 3D bioprinting for skin regeneration and describes potential improvements for clinical applications, but it reports no new experimental results.
47 citations
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November 2012 in “Pharmaceutical research” This study found that surface modified nanoparticles showed increased skin permeation and improvement in allergic contact dermatitis, independent of the follicular pathway.
43 citations
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January 2007 in “Gynecological Endocrinology” This study found that 9 out of 12 women with acne or alopecia showed subjective improvement with finasteride treatment despite having normal free testosterone levels, suggesting a potential role of 5alpha-reductase activity.