The HAIR-AN Syndrome: A Case Report
January 1995
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The HAIR-AN Syndrome, affecting about 5% of hirsute women, was characterized by insulin resistance, elevated insulin levels, acanthosis nigricans, and hyperandrogenism. In this case report, a 21-year-old woman with secondary amenorrhea, hirsutism, and hyperpigmented skin changes was treated with oral contraceptives and spironolactone. After 9 months, she showed significant clinical and hormonal improvement.
