73 citations
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January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
62 citations
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August 2006 in “Journal of Chromatography B” This article reviews the challenges in studying keratin proteins and emphasizes the potential of modern proteomic techniques to advance their research, but it reports no new findings.
46 citations
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December 1998 in “Journal of Biological Chemistry” This study found that keratin 19, unlike keratin 14, forms less stable filaments with keratin 5, suggesting distinct assembly properties and potential unique roles in skin basal cells.
15 citations
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January 1988 Hair follicles have unique proteins that vary by species and are influenced by nutrition.
13 citations
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April 1997 in “Biochemical and Biophysical Research Communications” This study observed that insulin-dependent diabetes induces specific molecular changes in the keratin structure of hair, potentially offering a new way to study diabetic complications through easily accessible tissues.
3 citations
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May 2009 in “International Journal of Cosmetic Science” This study investigated the effects of different relaxer treatments on African-American hair, finding lab-made relaxer solutions caused less damage to hair topography than commercial systems.
2 citations
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May 2023 in “Cancer medicine” This review reports that KRT80 is overexpressed in various cancers, enhancing cancer cell proliferation, invasiveness, and migration, suggesting it as a potential therapeutic target, though more clinical studies are needed to fully understand its role in cancer prognosis.
2 citations
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February 2021 in “FEBS open bio” In this study, transfection experiments showed that mutations in the K85 gene affect filament formation with K35, which may impact hair formation related to ectodermal dysplasia.
December 2025 in “Biopolymers” This study found that chemically treated hair, particularly when subjected to both acid straightening and bleaching, experiences more significant structural damage when exposed to heat, highlighting key changes in both the internal and surface components of hair fibers.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
This study found that keratin intermediate filaments in the hair of patients with giant axonal neuropathy were structurally altered, resulting in hair that was stiffer, stronger, and more extensible.
March 2007 in “International Journal of Cosmetic Science” This study found that Indian and Chinese black hair, with higher melanin content, resist photochemical degradation better than European hair, which has lower melanin levels, when exposed to dry, hot climates.
20 citations
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January 2017 in “Experimental Dermatology” In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.
April 2025 in “International Journal of General Medicine” This study found that among COVID-19 patients, a higher presence of the G allele in the IFITM3 rs12252 polymorphism correlates with increased inflammatory markers and disease severity, noting higher ESR, CRP, Fibrinogen, LDH, and D-dimer levels in severe cases compared to mild ones.
July 2019 in “International Society of Hair Restoration Surgery” This course overview discusses educational sessions on hair restoration surgery and FUE techniques and reports no new research findings.
5 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
September 2017 in “Journal of Dermatology & Cosmetology” This study reports a case of frontal fibrosing alopecia associated with hepatitis C treatment involving interferon and ribavirin.
November 2023 in “International Journal of Pharmaceutics” This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.
3 citations
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February 2024 in “Journal of the American Academy of Dermatology” This source discusses that while oral JAK inhibitors are used for treating lichen planopilaris and frontal fibrosing alopecia, they carry significant risk of adverse events; two cases showed promising results using tofacitinib cream as a safer topical alternative.
13 citations
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January 2018 in “International Journal of Trichology” In this study, intralesional triamcinolone acetonide injections were associated with halting the progression of frontal fibrosing alopecia in female patients and showed minimal adverse effects, but the efficacy as sole therapy remains unclear pending further trials.
September 2024 in “Cermin Dunia Kedokteran” This research discusses Fahr syndrome, highlighting its association with abnormal brain calcifications and varied clinical symptoms in young to middle-aged adults. Diagnosis involves specific criteria and CT scans, but no specific treatment exists; therapy focuses on managing symptoms and underlying conditions.
May 2003 in “Hair transplant forum international” This program description outlines the Fellowship Training Program's goal of developing Fellows' skills in performing safe and aesthetically sound hair restoration surgery, reporting no new research findings.
23 citations
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January 2012 in “International Food Research Journal” This case report describes a 39-year-old woman whose dermatomyositis-systemic lupus erythematosus overlap syndrome symptoms resolved after switching to tofacitinib.
October 2022 in “The Laryngoscope” The InCISE score is a promising tool for assessing wound healing in head and neck surgery but needs more research for broader use.
September 2015 in “Journal of Steroids & Hormonal Science” This study reports a significant reduction in hair loss and other androgen-related signs in hyperandrogenism patients using inositol supplementation, although further research is needed to confirm these findings.
September 2024 in “BMJ Case Reports” This case report highlights an atypical presentation of favus in an immunocompetent adult, where a psoriasiform plaque over the 'bindi' area was successfully treated with systemic itraconazole, achieving complete resolution without relapse. Simple stains proved essential for diagnosis in this resource-limited setting.
September 2022 in “XXXIX Congresso Brasileiro de Reumatologia” In this case report, a 42-year-old woman with cutaneous dermatomyositis showed significant improvement, including reduction of erythema, pruritus, and scaling, after starting JAK inhibitor tofacitinib, especially when conventional systemic treatments failed and intravenous immune globulin wasn't viable.
February 2005 in “The Journal of Urology” This article evaluates sexual function using the International Index of Erectile Function in people taking finasteride for androgenetic alopecia but does not present new findings.
July 2008 in “Journal of the Islamic Medical Association of North America” This conference abstract outlines topics discussed at the International Conference of the Islamic Medical Association of North America and reports no new results.