Characteristics of KRT80 and Its Roles in Neoplastic Diseases

    May 2023 in “ Cancer medicine ”
    Xinyuan Wei, Jie Zhao, Hao‐Bin Tong … Fang Song
    Studysummary This review reports that KRT80 is overexpressed in various cancers, enhancing cancer cell proliferation, invasiveness, and migration, suggesting it as a potential therapeutic target, though more clinical studies are needed to fully understand its role in cancer prognosis.
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    Research cited in this study 6

    1. Characteristics of KRT80 and Its Roles in Neoplastic Diseases Cancer medicine · 2023
    2. The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia Current opinion in cell biology · 2012
    3. Against The Rules: Human Keratin K80 Journal of Biological Chemistry · 2010
    4. Characterization of New Members of the Human Type II Keratin Gene Family and a General Evaluation of the Keratin Gene Domain on Chromosome 12q13.13 Journal of Investigative Dermatology · 2005
    5. The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain Differentiation · 2004
    6. Genes for Intermediate Filament Proteins and the Draft Sequence of the Human Genome Journal of Cell Science · 2001

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    1. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002