6 citations
,
December 2021 in “Scientific Reports” This study found that inhibiting class I histone deacetylases in postnatal mouse dermal cells preserved their ability to induce hair follicles during culture by increasing specific gene expressions and activating the Wnt signaling pathway.
10 citations
,
September 2021 in “American Journal of Medical Genetics Part A” This study on Qatari patients with Woodhouse-Sakati syndrome highlights the high incidence and diverse clinical presentation due to a specific genetic variant, emphasizing early diagnosis for effective management.
7 citations
,
January 2018 in “PubMed” In this study, reduced serum levels of iron, copper, and calcium were associated with premature graying of hair, suggesting that supplementation might help, but more research is needed to fully understand the relationship.
3 citations
,
December 2024 in “International Journal of Dermatology” This review examined the psychological effects, mechanisms, health associations, and treatments related to premature hair graying, highlighting factors like genetics, oxidative stress, smoking, and diet, with the aim of enhancing understanding and addressing its broader implications.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.
2 citations
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November 2011 in “Pediatric dermatology” This correspondence addresses the diagnostic challenges in distinguishing between Marie-Unna Hereditary Hypotrichosis and Autosomal Recessive Hereditary Hypotrichosis with Woolly Hair, reporting no new clinical findings.
17 citations
,
March 2023 in “Journal of Clinical Medicine” This study found that using PRP injections in skin flap reconstructions and combining acellular dermal matrix with split-thickness skin grafts improved healing and reduced complications in the surgical treatment of hidradenitis suppurativa.
31 citations
,
January 2014 in “Journal of endocrinological investigation” This study reviewed Woodhouse-Sakati syndrome and found it consistently associated with hypogonadism, decreased IGF1, and frontotemporal alopecia, with additional symptoms like intellectual disabilities and diabetes in some patients.
38 citations
,
March 2019 in “International Wound Journal” In this study, a new cell-tissue technology using a patient's own skin to create a full-thickness skin autograft successfully treated a chronic wound larger than 200 cm², achieving complete functional skin coverage within 12 weeks and maintaining results at a 6-month follow-up.
13 citations
,
September 2022 in “Biomolecules” This study found that specific gene upregulations and mutations in hidradenitis suppurativa skin support the role of inflammation, altered epithelial differentiation, and metabolism dysregulation in the disease's pathogenesis.
9 citations
,
January 1998 in “Studia Anglica Posnaniensia: international review of English Studies” This review discusses the cellular and molecular basis of wound-induced hair neogenesis and its age-related changes, reporting no new clinical results but highlighting areas for future research.
24 citations
,
January 2017 in “Dermatology online journal” This review examines hormonal therapies, including finasteride, dutasteride, spironolactone, and oral contraceptives, for treating hidradenitis suppurativa, summarizing various clinical study outcomes but reporting no new clinical results.
3 citations
,
December 1982 in “Australasian journal of dermatology” This article reviews approaches to managing hirsutism but does not report new clinical findings.
127 citations
,
August 2016 in “The oncologist” This paper reviews adverse events related to hedgehog pathway inhibitors in advanced basal cell carcinoma patients, reporting no new clinical results but aiming to inform healthcare professionals for improved patient care.
2 citations
,
January 2000 in “Journal of Toxicologic Pathology” This study identified a single autosomal recessive gene responsible for hypotrichosis in a mutant rabbit strain, affecting hair growth and causing epidermal and hair follicle abnormalities.
16 citations
,
September 2020 in “British journal of dermatology/British journal of dermatology, Supplement” This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.
4 citations
,
November 2022 in “Acta dermato-venereologica” This study found that patients with hidradenitis suppurativa had lower trabecular bone score and total hip bone mineral density compared to controls, with a high prevalence of vitamin D deficiency.
11 citations
,
September 2010 in “American Journal of Medical Genetics - Part A” This study reports a mutation in the U2HR gene causing Marie Unna hereditary hypotrichosis in a Turkish family and notes eyebrow loss as a diagnostic clue.
September 2025 in “Wound Repair and Regeneration” This review discusses wound‐induced hair follicle neogenesis and its potential for developing therapies for scar formation, but reports no new clinical results.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.
April 2021 in “HIV & AIDS Review” This study reported that GA 0.1% spray led to only slight improvement in treating anogenital warts among HIV-positive patients over twelve weeks.
July 2016 in “Hair transplant forum international” This announcement provides updated information for members and participants of the 24th ISHRS World Congress of Hair Restoration Surgery, without reporting any new research findings.
7 citations
,
January 2015 in “Case reports in genetics” This case report illustrates how SNP array testing helped identify a DCAF17 mutation linked to Woodhouse-Sakati syndrome in consanguineous Qatari siblings with shared features including alopecia and hypogonadotropic hypogonadism.
April 2014 in “Zhonghua shiyan waike zazhi” This study found that follicular unit-like wigs made from a polycaprolactone matrix exhibited good histocompatibility in New Zealand white rabbits, with reduced inflammatory cell infiltration compared to a polypropylene matrix.
January 2002 in “Agritrop (Cirad)” This study found that mutations in exon 3 of the hr gene are strongly associated with congenital hypotrichosis in Valle del Belice sheep, suggesting a potential genetic link to the disorder.
This health hazard evaluation by NIOSH identified problems with ventilation and environmental control at a resort spa, potentially contributing to reported employee health complaints.
1 citations
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December 2025 in “Selçuk tıp dergisi/Selçuk Üniversitesi Tıp Fakültesi dergisi” In this cross-sectional study, researchers observed that patients with hidradenitis suppurativa, particularly women, had lower 2D:4D finger length ratios compared to healthy controls, suggesting a potential link to prenatal androgen exposure and disease severity, though further prospective research is needed to confirm this hormonal impact.
5 citations
,
September 2022 in “Journal of Investigative Dermatology” This review discusses factors affecting wound-induced hair neogenesis in mice and reports no new results; it aims to facilitate meaningful comparisons of experiments across different laboratories.
1 citations
,
February 2024 This study observed that men with anogenital warts had higher prevalence of HPV6/11 in their regional hair samples compared to healthy controls, and patients with HPV6/11-positive hairs were more likely to have visible warts at subsequent visits.
July 2024 in “Journal of Investigative Dermatology” JW0061 may be a new treatment for hair loss by promoting hair growth through WNT signaling.