Platelet-Rich Plasma and Acellular Dermal Matrix in the Surgical Treatment of Hidradenitis Suppurativa: A Comparative Retrospective Study

    March 2023 in “ Journal of Clinical Medicine ”
    Marcin Gierek, Agnieszka Klama‐Baryła, Wojciech Łabuś, Beata Bergler‐Czop, Kornelia Pietrauszka, Paweł Niemiec
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    Studysummary This study found that using PRP injections in skin flap reconstructions and combining acellular dermal matrix with split-thickness skin grafts improved healing and reduced complications in the surgical treatment of hidradenitis suppurativa. Our plain-language summary of this paper — not a Tressless recommendation.
    This retrospective study compared the effectiveness of platelet-rich plasma (PRP) and acellular dermal matrix (ADM) in the surgical treatment of hidradenitis suppurativa (HS) in 61 patients. The study found that PRP injections in skin flap reconstructions significantly reduced postoperative complications, with 0% complications in the PRP group compared to 13.04% in the non-PRP group. Additionally, ADM and split-thickness skin graft (STSG) co-grafts resulted in better healing outcomes and fewer complications than STSG alone, with shorter hospitalization times. The study concluded that PRP-assisted skin flaps and ADM-STSG co-grafts were effective options for HS surgical treatment, particularly in severe cases, and highlighted the importance of considering patient characteristics and surgical methods to minimize complications and improve recovery outcomes.
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