Histocompatibility of Improved Follicular Unit-Like Wigs for Hair Transplantation

    April 2014 in “ Zhonghua shiyan waike zazhi ”
    Jin Wang, Zhiqi Hu, Jing Ren, Chuanbo Feng, Zhidan Zhang, Yong Miao
    TLDR Improved wigs showed good compatibility and no adverse reactions after transplantation.
    The study aimed to improve follicular unit-like wigs for transplantation and assess their histocompatibility. Medical-grade polycaprolactone was used to create the wigs, which were implanted into the scalps of New Zealand white rabbits. Histological analysis showed that the improved wigs had a milder inflammatory response one week post-surgery, with fewer inflammatory cells (122.67 ±4.55) compared to the original wigs (143.33±16.42), with a significant difference (P<0.05). Over time, inflammatory cells decreased, and fibroblasts and collagen fibers increased, indicating good tissue compatibility for both wig types. By one month and six months post-surgery, the difference in inflammatory cell count between the two groups was not statistically significant. The improved wigs demonstrated good histocompatibility, providing a solid foundation for long-term transplantation research.
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