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PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Testosterone's muscle-building effects do not require its conversion to DHT.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

The exact causes of baldness are not fully understood, limiting treatment options.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Certain drugs change freshwater snail shells to a "banana" shape.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

*Laportea bulbifera* contains unique compounds that may help treat benign prostatic hyperplasia.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Gene differences may affect baldness treatment response in Korean men.