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The document explains how male reproductive hormones work and affect the body.

Erythropoietin helps hair grow and could be a potential treatment for hair loss.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.

All women with Polycystic Ovary Syndrome (PCOS) in a study had at least one skin disorder, with the most common being excessive hair growth, acne, dark skin patches, hair loss, and oily skin.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Gene variation affects prostate issues and hair loss.

Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Higher androgen levels do not cause baldness in men.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Certain gene variations might be linked to severe acne in women but not in men.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

Lower SHBG levels may increase the risk of PCOS.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Fish oil improves skin health in people with diabetes and high cholesterol.

The study concluded that both anti-Mullerian hormone and LH/FSH ratio are higher in women with PCOS and combining these markers with BMI could improve diagnosis accuracy.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.