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Father's finasteride use may affect son's fertility and testicular function.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

The document concludes that transsexual individuals often experience improved quality of life after transitioning, despite higher risks of psychiatric issues and mortality.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.