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Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Myc activation reduces skin stem cells by affecting cell adhesion.

The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Wnt signaling is crucial for skin development and hair growth.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Hairless protein can block vitamin D activation in skin cells.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

Apremilast may help treat hair loss in alopecia areata.

Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.

Cetaceans lost hair due to changes in the Hr and FGF5 genes.

Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.