1 citations
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May 2022 in “International journal of molecular sciences” This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.
April 2025 in “Dermatology Practical & Conceptual” This study found that erosive pustular dermatosis of the scalp is often misdiagnosed as squamous cell carcinoma, highlighting the importance of biopsy for accurate diagnosis.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.
20 citations
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December 2019 in “International Journal of Molecular Sciences” This study found that preconditioning adipose-derived stem cells with HB-EGF enhanced their ability to promote hair growth in vivo by increasing their motility, paracrine effects, and survival.
November 2022 in “Journal of Investigative Dermatology” This study reported that an HS-associated NCSTN mutation in iPSC-derived skin organoids led to altered hair follicle stem cell differentiation and increased expression of proteins linked to HS inflammation.
September 2019 in “Journal of Investigative Dermatology” This study found that using human induced pluripotent stem cells (iPSC) carrying the causal mutation of Epidermolysis Bullosa simplex provides a robust model for understanding its molecular mechanisms and testing potential therapeutic targets.
129 citations
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July 2019 in “Stem Cell Research & Therapy” This review examines the role of epidermal stem cells in wound healing, discussing their characteristics and mechanisms, but does not report new clinical results.
December 2004 in “Reproduction Fertility and Development” This study used porcine models to isolate and culture stem cells from brain and hair follicles, shedding light on differentiation processes and potential markers for stem cell compartments under lab conditions.
4 citations
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June 2021 in “Wounds-a Compendium of Clinical Research and Practice” This study observed that erosive pustular dermatosis of the scalp in elderly patients was effectively treated with high-potency topical steroids, with plasma and lymphocyte dermal infiltrates helping to confirm diagnosis.
44 citations
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January 2015 in “Development” This study reports that human epidermal neural crest stem cells from hair follicles can be quickly differentiated into highly pure human Schwann cells without genetic manipulation, suggesting their potential for therapeutic applications.
April 2017 in “Journal of Investigative Dermatology” The researchers reported that iPSCs derived from Sendai virus reprogrammed blood cells can mature into functional keratinocytes for up to 60 days, potentially offering new approaches for DEB treatment.
February 2020 in “International Journal of Research in Dermatology” This study emphasizes that erosive pustular dermatosis of the scalp is an underrecognized condition, and increased awareness and diagnosis can improve patient outcomes by preventing further scalp damage.
October 2023 in “Research Square (Research Square)” This study developed a composite product from decellularized human placental connective tissue matrix and placental extract, finding that the combination showed improved biochemical and mechanical properties compared to each component alone, suggesting its potential use for treating chronic and deeper wounds.
10 citations
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January 2013 in “Stem Cells and Development” This study suggests that dermal stem/progenitor cells can be enriched by intracellular granularity and display high proliferation and differentiation potential in vitro, distinguishing them from other fibroblasts and progenitors.
1 citations
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October 2023 in “PROTOPLASMA” 22 citations
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December 2013 in “Stem cells and development” This study found that treating skin wounds with a combination of epidermis-derived epithelial-like stem/progenitor cells and platelet-rich plasma improved tissue repair and increased vascularization and elastin content compared to platelet-rich plasma alone.
61 citations
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April 2023 in “Advanced Materials” This study introduced a viscoelastic dry electrode that successfully reduces motion artifacts in EP monitoring on hairy skin, maintaining stable performance for up to 48 days.
April 2025 in “Cellular and Molecular Biology” This study found that human dermal stem/progenitor cells demonstrated greater proliferation and differentiation potential than hair follicle dermal papilla cells, which showed increased expression of hair regeneration markers.
This study found that while educating healthcare providers significantly improved their knowledge of polycystic ovarian syndrome, it did not lead to better diagnosis or management outcomes in a free clinic setting.
July 2025 in “Journal of Cutaneous Pathology” In this case report, a newborn with Conradi-Hünermann-Happle syndrome was diagnosed through early skin biopsy, which revealed unique histopathological features, including dystrophic calcifications, confirming a pathogenic variant in the EBP gene.
2 citations
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January 2009 in “Human cell culture”
29 citations
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June 2017 in “Journal of Inherited Metabolic Disease” This review discusses the potential of using high-throughput and high-content screening methods for drug repositioning in rare diseases and reports no new results.
18 citations
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February 2022 in “Cell Death Discovery” In this study, researchers found that hair follicle-derived mesenchymal stem cells, modified to overexpress extracellular matrix protein 1, significantly improved liver function and reduced liver damage in cirrhotic mice by inhibiting hepatic stellate cell activation and TGF-β/Smad signaling.
3 citations
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January 2013 in “Journal of cosmetics, dermatological sciences and applications” This study found that the new HCC additive enhances the permeation of pigments and active ingredients into hair, suggesting potential use in developing functional cosmetic hair products.
30 citations
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June 2016 in “Journal of Human Genetics” This study found pathogenic mutations in genes EDA, EDA1R, and EDARADD in 101 out of 124 hypohidrotic ectodermal dysplasia patients, revealing 23 novel mutations and indicating genetic variability.
12 citations
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February 2013 in “The Open Stem Cell Journal” This article reviews the definitions, opportunities, advantages, and limitations of dental pulp stem cells and stem cells from human exfoliated deciduous teeth in tissue engineering and regenerative medicine, reporting no new clinical results.
5 citations
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December 2016 in “Microscopy Research and Technique” This study suggests that prenatal infusion of epidermal neural crest stem cells may improve certain neural markers and reduce cortical injury in a mouse model of methylazoxymethanol-induced malformations.
April 2026 in “Microsystems & Nanoengineering” This study developed HA-gel-dex hydrogels with enhanced ECM-like properties and functionality, showing promise for 3D bioprinting, tissue repair, and as wound dressings due to improved cell interaction, cytocompatibility, antimicrobial synergy, and wound healing in mice compared to traditional ECM bio-inks.
31 citations
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August 2019 in “Regenerative Medicine” This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.
44 citations
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July 2020 in “Stem Cell Research & Therapy” This review discusses recent advancements in the study and application of epidermal stem cells for wound healing and tissue engineering, without presenting new experimental findings.