Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study suggests that lower-dose ethinyl estradiol formulations and progestin-only contraceptives may offer safer options for managing PCOS in obese women due to minimal metabolic effects.

This study aims to assess how daily life factors affect sleep patterns and describe individual sleep changes across the year, with results to be published in future research.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.

This review discusses the multifactorial etiology of hypospadias, including genetic predispositions and possible environmental factors, and highlights the need for further studies on genetic and environmental contributions to its increasing prevalence, without presenting new findings.

This study demonstrates a method using intravital imaging to observe sensory hair-cell development and regeneration in zebrafish, which may facilitate assays for drug discovery related to aural function preservation.

In this study, researchers developed a method to automatically detect androgen receptor nuclear translocation in dermal papilla cells using fluorescence markers and image analysis, finding that the receptor's nuclear signal peaks about 20 minutes after DHT exposure.

This study introduces a method for long-term expansion of adult mouse epidermal stem cells in vitro using an organoid culture system that maintains the basal-apical organization.

This review highlights the importance of selecting high-quality bioassays in discovering bioactive compounds from marine sources, emphasizing their role in evaluating safety and efficacy during pharmaceutical, food supplement, and cosmetic development.

This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.

This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.

This study found that biomimetic dermal papilla spheres cultured in a specific microenvironment can partially restore hair-inducing ability in high-passage dermal papilla cells in nude mice, resembling the characteristics of primary cells.

This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.

This article reviews in-vitro and cell-free methods for assessing the efficacy of herbal ingredients in cosmetic formulations for skin health and hair growth, but it reports no new clinical results.

This study reported that discarded squid ink was used to develop a high-performance, environmentally friendly hair dye that offers a stable deep black color, UV protection, and preserves hair structure, while showing excellent biosafety in lab tests.

In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.

This study investigated a fat grafting technique (MID BACK) to enhance back muscle definition in patients undergoing liposculpture, reporting no adverse events and only minor complications, suggesting the method is safe and effective for improving muscular contours and correcting spinal asymmetries.

This study presents a novel hydrogel scaffold made from tilapia collagen, which when activated by ultrasound, reprograms macrophages to promote wound healing, enhance angiogenesis, and stimulate hair follicle regeneration, offering a potential new method for treating inflammatory wounds.

This review discusses the characteristics, extraction strategies, and potential applications of plant and algal lipid droplets but reports no new empirical findings.

This review reports on the principles, applications, and future potential of bioprinting technology in fields like tissue engineering and organ regeneration, highlighting recent advancements and identifying ongoing challenges and future directions that require collaborative efforts to fully realize the technology's capabilities.

This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.

This study explored a new dutasteride nanocarrier for alopecia therapy, concluding that ingredient concentration is key to achieving the optimal particle size, stability, and skin permeation for extended drug release.

This article highlights advances in various physiological studies, including vitamin E's potential to improve aging-related outcomes in mice, but does not present new experimental results.

This study provided an overview of skin organoids created from pluripotent stem cells, showcasing their potential in dermatologic research and future clinical applications, while noting challenges such as lengthy differentiation protocols that result in heterogeneous products.

This review summarizes advancements in biomedical engineering for hair follicle regeneration, highlighting strategies like cell transplantation and tissue engineering to reconstruct hair follicles, and discusses both their technical limitations and potential future innovations in regenerative medicine.

This study reviewed the progress in developing induced platelets from human stem cells as an alternative source to meet clinical demands, although challenges remain for large-scale production and clinical application.

This review discusses the potential of plant-derived nanovesicles as natural therapeutics and drug delivery platforms in cancer therapy, highlighting their versatility and promising applications, but reports no new clinical results.

This study found that LC-MS/MS assays provided more reliable and precise steroid measurements in human serum compared to traditional immunoassays, particularly at lower concentrations.

This review highlights how utilizing unconventional and non-traditional cell sources for cultivated meat production could overcome manufacturing challenges, with distinct biological advantages potentially improving bioprocess efficiency and enabling the creation of novel meat products, according to the authors.

This review examines the use of computer vision techniques, specifically deep learning architectures and image processing algorithms, for detecting and assessing skin conditions like vitiligo and dermatitis, and highlights the need for disease-specific datasets to improve automated diagnostic tools in dermatology.