Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays

    Valentin Braun, Hermann Stuppner, Lorenz Risch, Christoph Seger
    Studysummary This study found that LC-MS/MS assays provided more reliable and precise steroid measurements in human serum compared to traditional immunoassays, particularly at lower concentrations.
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    1. The Efficacy and Safety of 17α-Estradiol (Ell-Cranell Alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study Annals of Dermatology · 2012
    2. Comparison of the Efficacy and Safety of Topical Minoxidil and Topical Alfatradiol in the Treatment of Androgenetic Alopecia in Women Journal der Deutschen Dermatologischen Gesellschaft · 2007