Integration of Point-Of-Care Technology in the Decoding Process of Single Nucleotide Polymorphism for Healthcare Application

The document reviews the integration of point-of-care technology (POCT) with amplification techniques like allele-specific PCR, LAMP, and RPA for efficient and cost-effective genotyping of single nucleotide polymorphisms (SNPs) related to human diseases. These methods offer rapid, sensitive, and portable SNP detection, suitable for low-resource settings, and aim to make genetic screening more accessible. The review highlights advancements in DNA extraction using microfluidics and the development of portable POCT systems, enhancing the efficiency and accuracy of SNP recognition in healthcare applications.