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People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Melatonin may help treat PCOS symptoms in rats.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.

Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Teucrium polium extracts are non-toxic and effectively speed up wound healing.