Altered Autonomic Neural Control of the Cardiovascular System in Patients with Polycystic Ovary Syndrome

December 2007 in “ International Journal of Cardiology ”

Göknur Tekin, Abdullah Tekin, Esra B. Kılıçarslan, Bulent Haydardedeoglu, Tuna Katircibasi, Tolga Kocum, Tansel Erol, Yucel Colkesen, Alpay Turan Sezgin, Haldun Müderrisoğlu

polycystic ovary syndrome PCOS autonomic neural control cardiovascular system heart rate recovery systolic blood pressure parasympathetic activity sympathetic response heart rate variability

TLDR People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

In the 2008 study, researchers compared the cardiovascular autonomic neural control between 26 untreated PCOS patients and 24 healthy controls, finding significant differences indicative of altered autonomic function in the PCOS group. The PCOS patients showed a lower heart rate recovery at 1 minute post-exercise and higher systolic blood pressure at peak exercise and during recovery, suggesting reduced parasympathetic activity and heightened sympathetic response. Additionally, heart rate variability measures were significantly lower in the PCOS patients. These results imply that PCOS may be associated with an increased risk of developing cardiovascular issues due to abnormal autonomic regulation.

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Research cited in this study

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research Endothelial Dysfunction in PCOS: Role of Obesity and Adipose Hormones

155 citations, March 2006 in “The American Journal of Medicine”

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

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