Altered Autonomic Neural Control of the Cardiovascular System in Patients with Polycystic Ovary Syndrome

    December 2007 in “ International Journal of Cardiology ”
    Göknur Tekin, Abdullah Tekin, Esra B. Kılıçarslan, Bulent Haydardedeoglu, Tuna Katircibasi, Tolga Kocum, Tansel Erol, Yucel Colkesen, Alpay Turan Sezgin, Haldun Müderrisoğlu
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    Studysummary This study found that patients with polycystic ovary syndrome have reduced heart rate recovery, an exaggerated systolic blood pressure response to exercise, and decreased heart rate variability, implying possible autonomic dysfunction.
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    In the 2008 study, researchers compared the cardiovascular autonomic neural control between 26 untreated PCOS patients and 24 healthy controls, finding significant differences indicative of altered autonomic function in the PCOS group. The PCOS patients showed a lower heart rate recovery at 1 minute post-exercise and higher systolic blood pressure at peak exercise and during recovery, suggesting reduced parasympathetic activity and heightened sympathetic response. Additionally, heart rate variability measures were significantly lower in the PCOS patients. These results imply that PCOS may be associated with an increased risk of developing cardiovascular issues due to abnormal autonomic regulation.
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