4 citations
,
January 2011 in “Der Pharmacia Lettre” This study found that ethanolic extract of Hibiscus rosasinensis flowers may act as a hair growth retarding agent in female rats, potentially useful for hair removal products.
2 citations
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February 2021 in “Case reports in dermatological medicine” In this case series, the topical botanical formulation GASHEE demonstrated significant improvements in hair regrowth without adverse events among patients with hair loss, including cases where previous treatments had failed.
5 citations
,
July 2023 in “World Journal of Stem Cells” In a study using a rat model, researchers developed injectable hydrogels from antler reserve mesenchyme which enhanced regenerative healing of full-thickness cutaneous wounds by creating a fetal-like niche that increased stem cell presence and modulated gene expression related to wound healing.
10 citations
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January 1989 in “Archives of Dermatological Research” The method effectively analyzes human hair proteins, especially nonfilamentous ones.
18 citations
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December 2009 in “Canadian Journal of Animal Science” This study reports that BMP2 expression in goat skin is higher during late telogen and early anagen phases, indicating a potential role in hair follicle regeneration.
April 2021 in “Journal of Investigative Dermatology” This trial found that intradermal injections of the Hair Stimulating Complex were well-tolerated and effectively stimulated hair growth and prevented hair loss in male pattern baldness participants over 18 weeks.
1 citations
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June 2024 in “European Journal of Dentistry” This study found that human placenta extract may be a promising pulp-capping material, causing less intense chronic inflammation and thicker dentine bridge formation compared to mineral trioxide aggregate in dogs' teeth.
27 citations
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April 2020 in “PLoS ONE” In this study, RNA-Seq analysis identified 2717 genes differentially expressed between anagen and telogen hair follicle stem cells in cashmere goats, potentially involving several signaling pathways in vitro.
5 citations
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June 2018 in “Records of Natural Products” This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.
17 citations
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June 2019 in “BMC genomics” This study cataloged several long non-coding RNAs and microRNAs in cashmere goat dermal papilla cells, suggesting these non-coding RNAs may play a role in hair follicle stem cell activation and hair growth.
1 citations
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August 2023 in “Biomolecules & therapeutics” In this study, researchers found that recombinant human HAPLN1 promoted hair growth in mice and human hair matrix cells by activating specific signaling pathways, suggesting it may offer a potential hair loss treatment with fewer side effects than existing medications.
July 2025 in “Journal of Investigative Dermatology” Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.
8 citations
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February 2017 in “International journal of molecular sciences” This study found that the natural extract e-CAF promotes the proliferation and migration of human hair dermal papilla cells in vitro, suggesting potential benefits for skin regeneration and tissue repair.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” According to this study, human scalp hair follicles containing pluripotent stem cells demonstrated the ability to differentiate into cardiac muscle cells and other cell types, suggesting potential applications in heart and nerve regeneration.
11 citations
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January 2018 in “Royal Society Open Science” This study investigated the formation of Type III brush hair in Chinese Haimen goats and identified genetic factors that may involve heat stress in the process.
May 2023 in “International journal of pharmaceutical sciences and medicine” This study found that Helianthus annuus oil promoted hair growth in a testosterone-induced alopecia mouse model, with higher hair density observed compared to untreated mice, though it was less effective than the standard minoxidil treatment.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article summarizes the phytochemistry, preparation methods, applications, and potential therapeutic benefits of fenugreek-based hair oil, suggesting its use as a natural remedy for hair growth, scalp health, and conditioning, while also noting its safety and future potential in cosmetic and pharmaceutical formulations.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research formulated a herbal hair oil using ingredients like pumpkin seed, bhringraj, and amla to reduce DHT levels and stimulate hair growth, with findings suggesting that the product is stable, suitable for the scalp, and free from toxic chemicals.
8 citations
,
November 2019 in “International Journal of Morphology” This study found that using henna dye positively affected hair cuticula pattern and diameters compared to undyed hair, though the degree of change may vary based on hair phenotype and condition prior to treatment.
October 2025 in “Journal of the Korean Society of Cosmetology” This study found that applying a hair mist with dandelion extract before heat perming improved wave efficiency, tensile strength, and hair cuticle condition compared to a base mist or no pretreatment, demonstrating the extract's protective effects against heat damage.
This study found that applying an ethanol extract of Prasiola japonica improved hair regrowth, length, and follicular density in testosterone-induced hair loss conditions in mice, while also promoting dermal papilla cell proliferation and reducing dihydrotestosterone production, though effects were less pronounced than those of minoxidil.
This study found that ethanolic extract and fractions of Ceiba leaf tonic may enhance rabbit hair growth similarly to 2% minoxidil.
9 citations
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February 2022 in “BMC Genomics” This study examined gene expression in cashmere goats and identified key pathways and molecular regulators that influence hair follicle growth stages and melatonin's role in promoting cashmere growth.
2 citations
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June 2025 in “Molecules” This review highlights that extracts from *Hamamelis virginiana* (witch hazel) exhibit antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties in various studies, showing promise for future therapeutic use in dermatology and cosmetology, particularly for skin treatments.
8 citations
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June 2024 in “Pharmaceutics” This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.
December 2023 in “Journal of Food Science and Nutrition” In this animal study, rosehip seed oil applied to the skin of mice promoted hair regrowth by accelerating hair follicles' transition from resting to growth phases and increased hair follicle density, bulb size, and skin thickness, suggesting potential as a treatment for hair loss.
115 citations
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August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Human hair keratin can be used in many medical applications.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
68 citations
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February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that keratin films made from human hair can potentially substitute for human nail plates in drug permeability studies, but they show higher sensitivity to penetration enhancers compared to bovine hooves.