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    Glossary Heat Shock Proteins

    help cells survive stress by stabilizing and refolding damaged proteins

    Heat Shock Proteins (HSPs) are a group of proteins that are produced by cells in response to stressful conditions, such as elevated temperatures, toxins, or other environmental stressors. They function as molecular chaperones, helping to stabilize and refold damaged proteins, thereby protecting cells from stress-induced damage. HSPs are crucial for maintaining cellular function and integrity, and their role is significant in various biological processes, including protein homeostasis and the stress response.

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    1. Identification of androgen-regulated genes in SV40-transformed human hair dermal papilla cells Journal of dermatological science · 2003 · 12 citations
    2. Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2. PubMed · 1992 · 31 citations
    3. Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata Scientific Reports · 2018 · 19 citations
    4. Exploring the “Thyroid–Skin Connection”: Concepts, Questions, and Clinical Relevance Journal of Investigative Dermatology · 2009 · 49 citations
    5. Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat ( <i>Capra hircus</i> ) Royal Society Open Science · 2018 · 11 citations
    6. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    7. <i>AXR3</i>and<i>SHY2</i>interact to regulate root hair development Development · 2003 · 157 citations
    8. Analysis of the expression pattern of the carrier protein transthyretin and its receptor megalin in the human scalp skin and hair follicles: hair cycle-associated changes Histochemistry and cell biology · 2010 · 6 citations
    9. Human dermal fibroblast‐derived secretory proteins for regulating nerve restoration: A bioinformatic approach Skin Research and Technology · 2024 · 1 citations
    10. Exosomes as a novel pathway for regulating development and diseases of the skin (Review) Biomedical Reports · 2018 · 15 citations
    11. Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway ˜The œAmerican journal of pathology · 2009 · 137 citations
    12. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006 · 122 citations
    13. Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep BMC genomics · 2018 · 17 citations
    14. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008 · 90 citations
    15. Skipping of Exons by Premature Termination of Transcription and Alternative Splicing within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant PloS one · 2012 · 6 citations
    16. Identification of Candidate Genes for Min Pig Villi Hair Traits by Genome-Wide Association of Copy Number Variation Veterinary sciences · 2023 · 3 citations
    17. STUB1 mutations in autosomal recessive ataxias – evidence for mutation-specific clinical heterogeneity Orphanet Journal of Rare Diseases · 2014 · 65 citations
    18. Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine International Journal of Molecular Sciences · 2015 · 23 citations
    19. Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress PLOS genetics · 2014 · 88 citations
    20. Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor Springer eBooks · 2016
    21. Chrousos syndrome: from molecular pathogenesis to therapeutic management European Journal of Clinical Investigation · 2015 · 47 citations
    22. Benign Cutaneous Eruptions After Transplantation Springer eBooks · 2017
    23. The Dynamics of the Skin’s Immune System International Journal of Molecular Sciences · 2019 · 306 citations
    24. Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19 Pharmacological Reports · 2020 · 70 citations
    25. Adrenal causes of endocrine hypertension in childhood or adolescence Journal of Endocrinological Investigation · 2025
    26. Integrating multi-omics analyses of Nonomuraea dietziae to reveal the role of soybean oil in [(4′-OH)MeLeu]4-CsA overproduction Microbial Cell Factories · 2017 · 1 citations
    27. Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature 2020 · 15 citations
    28. AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells 2019 · 17 citations
    29. 74398 Oral Intake of Colostrum-Derived Bioactives for Hair and Skin: Integrating Mechanistic, Translational, and Clinical Evidence Journal of the American Academy of Dermatology · 2026
    30. Bacillus Calmette-Guerin (BCG) Site Reaction After Coronavirus Disease 2019 (COVID-19) mRNA Vaccination Indian Journal of Dermatology · 2023