In a human genetic study on hidradenitis suppurativa, researchers identified 12 genetic risk loci and found that CXCR4-CD74 signaling may play a key role in hair follicle inflammation, suggesting CXCR4 blockade as a potential therapeutic approach for this condition.
1 citations
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November 2024 in “Blood” This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.
18 citations
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August 1985 in “European journal of endocrinology” This study found that high-dose cyproterone acetate was effective for treating hirsutism, but 33% of patients felt their condition worsened on low-dose maintenance therapy, despite no significant change in objective measures of hair growth.
7 citations
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December 2014 in “Gynecological Endocrinology” This study found that LC-MS/MS is a more reliable method than immunoassays for measuring serum 17OHP and androgen levels in women with hyperandrogenism.
October 2022 in “Dermatology practical & conceptual” This study found that bipolar disorder is more prevalent in patients with hidradenitis suppurativa than in those with psoriasis or in control groups.
August 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that Hydroxypinacolone Retinoate (HPR) may alleviate UV-induced skin photoaging by enhancing collagen synthesis, reducing degradation, and modulating inflammatory and oxidative responses in a dose-dependent manner.
4 citations
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November 2003 in “Hair transplant forum international” This abstract mentions that using magnification during follicular unit graft dissection in hair restoration is known to reduce transection and increase graft yield, but does not report on new findings itself.
1 citations
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November 2022 in “International journal of molecular sciences” This study found that local injections of fetal tissue mesenchymal stromal cells in mice significantly improved healing and hair follicle density after high-dose radiation-induced skin damage.
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may help treat hidradenitis suppurativa.
9 citations
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August 2015 in “Tissue Engineering and Regenerative Medicine” In this study, human dermal stem/progenitor cell-derived conditioned medium was found to promote hair regrowth in mice, possibly through effects on the Wnt/β-catenin pathway.
28 citations
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October 1992 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this study, Scalp Immersion Proxigraphy (SIP) was shown to produce more accurate measurements of linear hair growth rate than crude phototrichogram techniques, suggesting SIP's suitability for clinical trials monitoring hair growth.
April 2017 in “Journal of Investigative Dermatology” Applying pseudoceramide improved skin and hair health.
November 2024 in “Journal of Investigative Dermatology” ATP-sensitive potassium channels are important for hair growth.
68 citations
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August 2014 in “Stem Cells Translational Medicine” This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.
15 citations
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November 2024 in “Materials” This review discusses the medical and dental applications of polyhydroxyalkanoates (PHAs), highlighting their potential for improving drug delivery and providing biocompatible solutions for medical devices, but reports no new clinical results.
10 citations
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January 2018 in “Postępy Dermatologii i Alergologii” This study found that 21 out of 39 patients with alopecia areata experienced more than 50% hair regrowth after six months of DPCP treatment, with better outcomes observed in those treated at 3-week intervals compared to weekly intervals.
September 2010 in “대한화장품학회지(J. Soc. Cosmet. Scientists Korea)” This study developed and validated a method to analyze active ingredients in hair nourisher products, which was successfully applied to products from the market.
2 citations
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December 2021 in “Journal of Cosmetic Dermatology” This review analyzes existing literature on platelet-rich plasma for hair loss, discussing its mechanisms and preparation, but reports no new clinical results and highlights the inconsistency of current evidence.
July 2017 in “Skin appendage disorders” Platelet-Rich Plasma (PRP) is becoming popular for treating hair loss and it's important for dermatologists to understand how it works and its safety.
37 citations
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February 2009 in “Bioorganic & Medicinal Chemistry” This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.
40 citations
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June 2013 in “Biomaterials” This study developed a 3D engineered hair follicle model that mimics the native hair bulb and may aid in drug screening for hair growth therapies.
3 citations
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August 2018 in “Stem cells international” This study found that cultured hair follicle dermal cells support maintenance and potentially aid in the clinical application of pluripotent and haematopoietic stem cells.
3 citations
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June 2022 in “European journal of human genetics” This study reports the first cases of recessive KRT17-related pachyonychia congenita involving all ectodermal derivatives in seven members of two consanguineous Pakistani families.
8 citations
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April 1997 in “Experimental Dermatology” This study found that hHbl gene expression is localized in the cortical cells of the human hair shaft and is notably high in pilomatricoma cells transitioning to hair shaft keratinocytes.
20 citations
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June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.
January 2011 in “Annals of dermatology/Annals of Dermatology” During treatment with interferon/ribavirin for hepatitis C, this study observed significant and lasting improvement in a patient's psoriasis without additional psoriasis-specific therapies.
June 2022 in “Plastic and reconstructive surgery. Global open” This study found that platelet-rich plasma treatment significantly improved patients' quality of life and emotional well-being 3-5 months after treatment for hair loss.
2 citations
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March 2019 in “Experimental Techniques in Urology & Nephrology” This article reviews the dermatologic conditions associated with hemodialysis, such as pruritus, xerosis cutis, and skin infections, and does not present new findings.
11 citations
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March 2014 in “Journal of Investigative Dermatology” In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.
January 2021 in “Victoria University Research Repository (Victoria University)” This study concluded that high-intensity interval training (HIIT) offers superior benefits over standard moderate-intensity continuous training (MICT) in improving aerobic capacity, insulin sensitivity, hormonal profiles, and anxiety scores in overweight women with PCOS.