Efficacy of Diphenylcyclopropenone in Alopecia Areata: A Comparison of Two Treatment Regimens

January 2018 in “ Postępy Dermatologii i Alergologii ”

Danuta Nowicka, Joanna Maj, Alina Jankowska‐Konsur, Anita Hryncewicz-Gwóźdź

diphenylcyclopropenone alopecia areata hair regrowth DPCP AA

TLDR Treating alopecia areata every 3 weeks with diphenylcyclopropenone is more effective than weekly treatments.

This study evaluated the efficacy of diphenylcyclopropenone (DPCP) in treating alopecia areata (AA) by comparing two treatment regimens in 39 patients. Group A received weekly treatments, while Group B received treatments every 3 weeks. After 6 months, 21 patients experienced hair regrowth greater than 50%, with Group B showing higher efficacy (54%) compared to Group A (46%). The study suggested that longer intervals between treatments might be safer and more comfortable for patients, though further research was needed.

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