1 citations
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January 2019 in “PubMed” This study found no correlation between androgenic alopecia and lower urinary tract symptoms or prostate volume in men who underwent a Green Light Laser Vaporization Procedure of the prostate.
This study found a significant association between lower vitamin D levels and increased severity of androgenetic alopecia in men.
This study found that metabolic syndrome is more common in individuals with androgenic alopecia compared to those without, and that free androgen index could help identify those with the syndrome.
April 2019 in “Advances in Cosmetic Surgery” The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.
December 2018 in “Neuroradiology” MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.
March 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” In this study, researchers compared the efficacy of platelet-rich plasma with microneedling versus microneedling alone for treating androgenic alopecia in 50 patients, though results are not reported in the abstract.
May 2020 in “Journal of Asian Medical Students' Association” This study concluded that psychological well-being and self-image among Filipino males with androgenetic alopecia may be influenced by age, education level, and disease severity.
June 2019 in “Brain Imaging and Behavior” In this study, androgenic alopecia was identified as an independent predictor of abnormal white matter hyperintensities in the brain, suggesting it may serve as a surrogate marker for cerebral small vessel disease linked to arteriolosclerosis.
38 citations
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September 2006 in “Journal of Dermatological Science” This study evaluated the effect of 2% ketoconazole lotion for androgenetic alopecia, but the results regarding its effectiveness on clinical appearance remained unclear.
20 citations
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July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
4 citations
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February 2021 in “International Journal of Dermatology” This study found that increased levels of PGD2 and prostacyclin and decreased levels of PGE2 and PGF2α were associated with baldness in androgenetic alopecia, suggesting potential targets for treatment.
226 citations
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September 2001 in “Journal of The American Academy of Dermatology” Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
130 citations
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May 1988 in “Journal of The American Academy of Dermatology” This study found that frontal and frontoparietal hair recession is relatively common in women, especially after menopause, and may not indicate abnormal androgen metabolism absent other virilization signs.
92 citations
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October 2002 in “Journal of The American Academy of Dermatology” This study reports that oral finasteride improved or stabilized hair loss in women with hyperandrogenism but not in postmenopausal women with female pattern hair loss.
91 citations
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May 2003 in “American Journal of Pathology” This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.
88 citations
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October 2002 in “Journal of Dermatology” In this study, 19 patients treated with finasteride for androgenetic alopecia developed moderate to severe depression, which resolved after stopping the medication, suggesting an association between finasteride and mood disturbances.
73 citations
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June 2001 in “Endocrinology” In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.
56 citations
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June 2001 in “European journal of cardiovascular prevention & rehabilitation” This study found that men with early-onset androgenic alopecia have a higher risk of needing coronary revascularization before age 60 compared to those with later onset or no hair loss.
56 citations
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November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
54 citations
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May 1998 in “Urology” This study demonstrates that patients with benign prostatic hyperplasia have a higher severity and frequency of male pattern baldness compared to a control group.
53 citations
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November 2006 in “Journal of Endocrinology” This study found that prolactin plays a direct role in regulating the timing of hair growth cycles in mice by affecting the skin, rather than through other endocrine factors.
45 citations
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September 2018 in “International Journal of Women's Dermatology” This review discusses the use of platelet-rich plasma as a treatment for androgenetic alopecia and highlights the need for standardized protocols, reporting no new clinical results.
44 citations
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March 1987 in “Journal of The American Academy of Dermatology” This study found that both 2% and 3% topical minoxidil were more effective than placebo in promoting hair growth for men with male pattern baldness over 12 months.
34 citations
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February 2013 in “Journal of The American Academy of Dermatology” This meta-analysis found that vertex pattern androgenetic alopecia was associated with an increased risk of developing prostate cancer, while other androgenetic alopecia patterns did not show a significant link.
33 citations
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November 2012 in “Journal of The American Academy of Dermatology” This study reported that female pattern hair loss was prevalent in 11.8% of women aged 30 and older and was associated with high fasting glucose, fewer childbirths, oral contraceptive use, and excessive ultraviolet exposure.
31 citations
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January 1989 in “Clinical and Experimental Dermatology” In this study, topical 2% minoxidil did not significantly improve hair density measures in men with male pattern baldness, although there was no deterioration, suggesting a potential prophylactic effect.
30 citations
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January 2014 in “Annals of Dermatology” This study observed no significant relationship between trichoscopic findings and disease severity in male or female androgenetic alopecia, despite some specific patterns correlating with different severity levels in female patients.
20 citations
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January 2012 in “Journal of Steroids & Hormonal Science” The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
19 citations
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August 1993 in “Journal of Cutaneous Pathology” In this study, researchers found that as androgenetic alopecia severity increased, the hair follicle matrix and dermal papilla's volume and cell nuclei number decreased, especially in the papilla.
18 citations
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March 2008 in “British Journal of Dermatology” This study found that finasteride 1 mg daily decreased 5alpha-dihydrotestosterone levels and improved hair growth in younger men with androgenetic alopecia, with higher initial hormone levels predicting better response.