Is There an Association Between 25(OH)D Serum Levels and Vitamin D Status with the Severity of Androgenetic Alopecia in Men?

This study found that vitamin D deficiency was significantly more prevalent among men with androgenetic alopecia in eastern Uttar Pradesh, India, than in age-matched controls, suggesting a potential link between vitamin D levels and the condition's pathogenesis.

In this study on male androgenetic alopecia, the researchers reported significant increases in hair count, density, and thickness with minimal side effects over 6 weeks using adipose-derived stem cell conditioned media and minoxidil, but found no significant differences between concentrated and non-concentrated treatments.

In this study, no significant association was found between the severity of androgenetic alopecia in males and trichoscopy features such as hair diameter diversity, vellus hair, and white dots, suggesting that trichoscopy may not predict alopecia severity based on the Hamilton–Norwood scale.

This study found that at Dr. Cipto Mangunkusumo National General Hospital in Jakarta, alopecia areata was the most prevalent hair disorder, followed by alopecia androgenetic and telogen effluvium, each with distinct socio-demographic profiles.

This study identified clinical features and genetic variants associated with early onset female pattern hair loss, highlighting decreased hair shaft density and specific SNPs related to androgenic features.

This review discusses vitamin D's role in hair follicle biology and its association with hair loss but reports no conclusive evidence for its effectiveness as a treatment, indicating the need for further studies.

This study found that vitamin D levels were significantly lower in men with androgenetic alopecia compared to healthy controls, while ferritin levels showed no significant difference.

This source reviews treatments for androgenetic alopecia, highlighting that combining therapies generally improves effectiveness over single treatments, and discusses emerging drug-assisted delivery techniques aimed at increasing the efficiency of conventional drugs like minoxidil and finasteride.

This study found a significant correlation between vitamin D deficiency and the severity of androgenetic alopecia in males, suggesting that vitamin D may influence the condition's premature onset.

This study found that individuals with androgenic alopecia had higher levels of vitamin D compared to those with telogen effluvium and healthy controls.

This study found that 64.8% of patients with different types of alopecia had vitamin D deficiency, and those with lichen planopilaris and telogen effluvium had higher odds of severe deficiency compared to patients with alopecia areata.

This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.

This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.

This study suggests that lower serum and tissue vitamin D receptor levels in alopecia areata and androgenetic alopecia patients may play a role in the pathogenesis of these hair diseases.

This study found no significant association between androgenetic alopecia and metabolic syndrome, though systolic blood pressure was higher in the alopecia group compared to controls.

This study found that higher BMI was significantly associated with more severe hair loss in men with male-pattern and early-onset androgenetic alopecia.

This study suggests the average age of onset for androgenic alopecia may be decreasing, but a longer-term study is needed to confirm this observation.

This study observed that smokers and alcohol consumers with androgenetic alopecia had significantly lower serum levels of antioxidant vitamins, and these habits may trigger earlier onset of alopecia in susceptible individuals.

This study found no significant association between the degree of male-pattern baldness and serum 25-hydroxyvitamin D levels in healthy middle-aged and older men.