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This study found that the CD44(+) ALDH(+) population of neonatal human keratinocytes exhibited enhanced stem cell properties, including significantly increased long-term epidermal regeneration and multipotency, compared to unfractionated cells.

Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This review explores recent findings on the roles of melanocyte and melanocyte stem cells in the hair follicle, highlighting their importance for skin health and potential applications in regenerative medicine, but reports no new clinical results.

This review explores regenerative medicine approaches for vitiligo and alopecia areata, focusing on pathways for repopulating melanocytes and regrowing hair follicles, and summarizes potential treatments without reporting new clinical results.

This study reports that the side population technique can isolate melanocyte stem cells from human hair follicles, potentially allowing them to be used for skin pigmentation repopulation.

This study describes the process of isolating and analyzing multipotent stem cells from mouse hair follicles for potential use in tissue engineering and regenerative medicine.

In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.

This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.

This study suggests that different melanocyte subpopulations in hair follicles have varying patterns of apoptosis and survival during the catagen phase, which may inform models for modulating melanocyte behavior in vivo.

This chapter reviews recent developments in vitiligo research, highlighting the role of melanocyte stem cell differentiation and oxidative stress in its management, but reports no new clinical results.

This case report documents an 8-year-old boy with alopecia areata presenting as symmetric alopecic patches with a triangular and targetoid pattern on the scalp, successfully treated with clobetasol propionate foam.

This review describes the hair follicle's structure, particularly its role as a stem cell niche, and discusses its potential application in skin tissue engineering, but does not present new research findings.

This research reported that dermal progenitor cells can enhance split-thickness skin graft outcomes by improving dermal layer qualities and reducing itch and offer potential in skin wound healing using a flowable hydrogel for better cell delivery and survival.

Choose between topical and oral minoxidil for hair growth based on personal tolerance and side effects.

Tofacitinib partially improved hair regrowth in a patient with severe hair loss.

This study suggests that hepatocyte growth factor (HGF) may play a role in hair follicle neogenesis and that an HGF mimetic could enhance skin substitute development.

This study reveals that hair follicles in mice and humans recruit epidermal Langerhans cells during skin inflammation via specific chemokine signaling pathways.

This study found that platelet-derived growth factor signaling is crucial for maintaining the hair follicle dermal stem cell pool and supporting their regenerative capacity.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.

This study found that Wnt signaling in the hair follicle is crucial for coordinating the behavior of epithelial and melanocyte stem cells, which drives hair regeneration and melanocyte differentiation in mice.

This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.

In this study, ACF sponges with 10% fucoidan significantly promoted wound healing and hair follicle regeneration in rats, showing improved hemostatic and antibacterial performance compared to other formulations.

This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.

This review revisits the mechanisms of wound induced hair follicle neogenesis in mice and concludes that the process involves canonical WNT signaling activated by Fgf9 from γδ T cells, but more research is needed to fully understand its cellular bases.

This review discusses emerging targets for developing drugs to treat hair loss and reports no new clinical results; the authors emphasize the potential for therapies that regenerate hair follicles.

In this study, overexpression of Wnt5a in mice was associated with the elongation of the telogen stage and inhibition of hair growth initiation, suggesting Wnt5a's role in maintaining hair follicle quiescence.

This review discusses the multifaceted roles of hair follicles in skin health, including potential contributions to skin neoplasias, and reports no new results.