A Case of Alopecia Areata with Paradoxical Spontaneous Repopulation and Good Response to Clobetasol Propionate

    February 2017 in “ Medicina cutánea ibero-latino-americana ”
    Felipe César Benavente Villegas, Francisco José Ferrando Roca
    Image of study
    TLDR An 8-year-old boy with hair loss had hair regrowth and responded well to clobetasol propionate treatment.
    The document presents a case of an 8-year-old male patient with alopecia areata (AA), an autoimmune condition causing localized hair loss, who experienced paradoxical hair regrowth and responded well to treatment with clobetasol propionate. The patient had symmetrical alopecic patches in a triangular and targetoid pattern, primarily affecting the left fronto-parieto-temporo-occipital area of the scalp. Histology confirmed the diagnosis of AA. Treatment with clobetasol propionate foam at a dose of 500 µg applied at night on alternate weeks resulted in partial hair regrowth at the three-month follow-up and complete hair regrowth after six months, with no associated adverse effects. This case highlights the occurrence of spontaneous paradoxical repopulation in AA and the effectiveness of high-potency topical corticosteroids in such atypical presentations of hair loss.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 3 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community My experience and a discourse on “DUPA”

      in Chat  46 upvotes 2 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community 10 months CB and Oral Minoxidil

      in Progress Pictures  110 upvotes 8 months ago
      A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 6 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

    Similar Research

    5 / 1000+ results