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A Case of Alopecia Areata with Paradoxical Spontaneous Repopulation and Good Response to Clobetasol Propionate

research Un caso de alopecia areata con repoblación paradójica espontánea con buena respuesta a propionato de clobetasol

February 2017 in “Medicina cutánea ibero-latino-americana”

This case report documents an 8-year-old boy with alopecia areata presenting as symmetric alopecic patches with a triangular and targetoid pattern on the scalp, successfully treated with clobetasol propionate foam.

research Alopecia and Hair Damage Induced by Oncological Therapy

7 citations , October 2019 in “Klinická onkologie”

This review discusses the impact of oncological therapy on hair loss, highlighting that while most alopecia is reversible, it can be permanent depending on treatment type and factors.

research Medical-Cosmetic Devices for Home Use: Present and Future Considerations

2 citations , May 2010 in “Actas Dermo-Sifiliográficas”

This article reviews home-use laser and intense pulsed light systems for hair removal and growth, noting limited efficacy and safety data and emphasizing the need for long-term studies.

research Unusual forms of alopecia areata in a Trichology Unit

7 citations , August 2013 in “Journal of the European Academy of Dermatology and Venereology”

This study reported that atypical variants of alopecia areata made up less than 25% of all cases in their specialized trichology unit, suggesting a potential selection bias.

research Valproic acid and alopecia: A two-edged sword

2 citations , April 2017 in “Asian Journal of Psychiatry”

This review discusses the role of histone deacetylases in hearing loss, proposing potential pharmacological interventions, but reports no new clinical results.

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Community Join

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community Has anyone’s hair improved/saw more regrowth/thickening after quitting smoking cigarettes.

12 upvotes 2 months ago

Quitting smoking may improve hair quality and overall health, but it is not a standalone solution for reversing hair loss. Treatments like finasteride and minoxidil are more effective for hair regrowth, while smoking can exacerbate hair loss by increasing DHT and affecting scalp health.

community Fix/min after 9 months - can you spot the difference?

in Is this regrowth? 141 upvotes 8 months ago

The user experienced significant hair regrowth after using minoxidil for 9 months and finasteride for 3 months, with plans to continue treatment and possibly get a hair transplant. Some users suggested adding microneedling and other treatments, while others discussed potential side effects of finasteride.

community 3 months 5g Min only before/after, 26 y/o

in Is this regrowth? 451 upvotes 1 year ago

The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.

community 2 years fin only 1mg/daily + 4 months of gradually introducing Dut 0.5mg/daily

1706 upvotes 11 months ago

A user experienced significant hair regrowth using finasteride 1 mg daily for two years and gradually introduced dutasteride 0.5 mg daily over four months. They reported no side effects and plan to switch fully to dutasteride due to its cost-effectiveness and potential effectiveness.

community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 130 upvotes 1 year ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

learn Verteporfin

chemical that might completely regrow follicles from hair transplant extractions

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Setipiprant

How does Setipiprant work on the scalp to potentially promote hair regrowth? Setipiprant blocks the DP2 (CRTH2) receptor that prostaglandin D₂ acts through, and PGD₂ is reported to be elevated in balding scalp — but the one published placebo-controlled trial in men (DuBois 2021, n=169) found no significant hair regrowth. It is an experimental compound, not an approved hair-loss medicine.

learn Rapamycin

Does topical rapamycin actually help reactivate dormant hair follicles? Topical rapamycin may help reactivate dormant hair follicles, but evidence is still emerging.

learn Redensyl

Redensyl, Capixyl, Procapil, Anagain, and Baicapil: the wonder group of hair loss products. Redensyl, Capixyl, Procapil, Anagain, and Baicapil are promising alternatives for hair loss treatment.

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

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