Topical Minoxidil or Oral Minoxidil in Alopecia: What Is Your Choice?

The document discussed the use of topical versus oral minoxidil for treating alopecia. Topical minoxidil was widely used and approved by the FDA for both men and women, showing significant efficacy in increasing hair growth and thickness, with a 45% repopulation rate at 16 weeks. However, its effects were temporary and required continuous use. Oral minoxidil, although not officially indicated for alopecia, was considered for patients who could not tolerate topical application. A study comparing oral and topical minoxidil in women found similar efficacy but different side effect profiles, with oral minoxidil causing more systemic effects like hypertrichosis and increased heart rate. The choice between oral and topical forms should be made collaboratively between the dermatologist and patient, weighing the benefits and risks of each option.