Bio-Multifunctional Alginate/Chitosan/Fucoidan Sponges with Enhanced Angiogenesis and Hair Follicle Regeneration for Promoting Full-Thickness Wound Healing

    June 2020 in “ Materials & Design
    Yuanping Hao, Wenwen Zhao, Liyu Zhang, Xi Zeng, Zhan-Yi Sun, Demeng Zhang, Peili Shen, Zhixin Li, Yantao Han, Peifeng Li, Qihui Zhou
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    Studysummary In this study, ACF sponges with 10% fucoidan significantly promoted wound healing and hair follicle regeneration in rats, showing improved hemostatic and antibacterial performance compared to other formulations.
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    The study developed a bio-multifunctional alginate/chitosan/fucoidan sponge for wound healing. The sponge showed excellent hemostatic and antibacterial properties and promoted full-thickness wound healing by reducing inflammation, facilitating epithelialization, and enhancing angiogenesis and hair follicle regeneration. The study suggests that ACF sponges could be a promising candidate for wound healing applications.
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