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Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.

Minoxidil may help reduce aging effects in brain cells.

Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.

UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.

Neuregulin3 affects cell development in the skin and mammary glands.

Human skin has less GDNF and its receptor with age.

Type 2 cytokines IL-4 and IL-13 increase skin's vulnerability to Staphylococcus aureus, which could be important for treating atopic dermatitis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.

Probiotics show promise for health benefits but need more research to understand how they work.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Both cell and non-cell parts are important for rat whisker follicle regrowth.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.

Sugars from Sargassum and brown algae may have health benefits like fighting viruses and helping with wound healing, but there are challenges in using them.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.

Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.

Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.