1 citations,
September 2023 in “eLife” TLR2 is important for hair growth and can be targeted to treat hair loss.
1 citations,
January 2019 in “Skin Pharmacology and Physiology” Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.
1 citations,
January 2001 in “Cosmetics and toiletries” Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
June 2024 in “International Journal for Research in Applied Science and Engineering Technology” Flaxseed hair gel is effective for hair growth and dandruff, is stable, and has minimal side effects.
April 2024 in “Frontiers in physiology” Immune cells are crucial for hair growth and preventing hair loss.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
September 2023 in “Journal of microbiology and biotechnology” A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
April 2018 in “Journal of Investigative Dermatology” Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.
April 2017 in “Journal of Investigative Dermatology” The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
157 citations,
April 1994 in “Clinical endocrinology” Androgens can cause hair growth in some areas and hair loss on the scalp.
117 citations,
August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
48 citations,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
April 2017 in “Journal of Investigative Dermatology” April 2018 in “Journal of Investigative Dermatology” 47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
August 2016 in “Journal of Investigative Dermatology” DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
September 2017 in “Journal of Investigative Dermatology” Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink, leading to skin issues, and blue light can help hair grow.
8 citations,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
1 citations,
November 2014 The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.
September 2019 in “Journal of Investigative Dermatology” Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
October 2023 in “Research Review” Some skin tumors from hair follicles and glands can be linked to genetic syndromes and may be benign or malignant.
59 citations,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
36 citations,
May 2015 in “Australasian Journal of Dermatology” Low dose oral minoxidil helps regrow hair in permanent chemotherapy-induced alopecia.