research Mechanisms of Tolerance and Potential Therapeutic Interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
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research ELife Assessment: The Drosophila Hematopoietic Niche Assembles Through Collective Cell Migration Controlled by Neighbor Tissues and Slit-Robo Signaling
Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
research Regeneration, Wound Healing, and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
research Advancing Skin Model Development: A Focus on a Self-Assembled, Induced Pluripotent Stem Cell-Derived, Xeno-Free Approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
research Fatal Autoimmunity Results from the Conditional Deletion of Snai2 and Snai3
Deleting Snai2 and Snai3 causes fatal autoimmunity.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Blimp1+ Cells Generate Functional Mouse Sebaceous Gland Organoids In Vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
research Cytostatics and Immunosuppressive Drugs: Toxicities and Management
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research Stem Cell Therapy for Burns: The Story So Far
Stem cell therapy shows promise in improving burn wound healing.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells
SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
research Are Fingernails a Key to Unlocking the Puzzle of Mammalian Limb Regeneration?
Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
research Dedifferentiation of Committed Epithelial Cells Into Stem Cells In Vivo
Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
research Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia
The local environment is crucial for cell development in the tongue.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research The Role of Pannexin 3 in Bone Biology
Pannexin 3 is important for bone formation and the development of bone cells.
research Role of Stem/Progenitor Cells in Reparative Disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Calcium Regulation of Stem Cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research TGF-β Family Signaling in Stem Cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Stem Cell Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
research Isolation of Epithelial Stem Cells from Dermis by a Three-Dimensional Culture System
Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
research Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications
Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.