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Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.

WNT signaling is crucial for skin development and healing.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Immune cells are essential for skin regeneration using biomaterial scaffolds.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

BMP signaling is essential for the development of touch domes.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Different types of skin cells play specific roles in development, healing, and cancer.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

CD4+ skin cells may be precursors to basal cell carcinoma.

Lymphatic vessels are important for skin repair and could affect skin disease treatments.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.

The research identified genes that explain why some sheep have curly wool and others have straight wool.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

The study developed a new way to create hair-growing tissue that can help regenerate hair follicles and control hair growth direction.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.