research A Simple Non-Invasive Approach Toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System
A new method for delivering drugs through the skin using biodegradable particles was found to be effective.
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research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream
Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
research Keratin Disorders: From Gene to Therapy
New treatments targeting specific genes show promise for treating keratin disorders.
research Would You Recognize This Lesion as a Gumma Syphilitica?
LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
research Activity of Type 1 5α-Reductase Is Greater in the Follicular Infrainfundibulum Compared with the Epidermis
The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
research Basal Cells in the Epidermis and Epidermal Differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research Hidradenitis Suppurativa: A Chronic Inflammatory Skin Condition
Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
research Polyclonal Origin and Hair Induction Ability of Dermal Papillae in Neonatal and Adult Mouse Back Skin
Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
research Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in Alopecia Areata
Tiny particles from umbilical cord stem cells may help hair grow back in a type of hair loss.
research Androgenetic Alopecia: Mechanisms and Progression
Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.
research Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-option in the Evolution of the Hair Follicle
Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.
research Expression of the Heat Shock Protein-27 in the Adult Human Scalp Skin and Hair Follicle: Hair Cycle–Dependent Changes
Heat shock protein 27 is more present in the active growth phase of human scalp hair follicles.
research The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure
Hair follicles help skin immune recovery after UVB exposure.
research Stimulation of Hair Growth Effect by Fermented Ginsenosides Using Levilactobacillus Brevis THK-D437
Fermented ginsenosides from kimchi bacteria may promote hair growth better than finasteride.
research Effects of Photoperiod on Nutrient Digestibility, Hair Follicle Activity, and Cashmere Quality in Inner Mongolia White Cashmere Goats
Short daily photoperiods improve cashmere production in Inner Mongolia white cashmere goats.
research Platelet-Rich Plasma as a Novel Treatment for Lichen Planopillaris
Platelet-rich plasma may successfully treat lichen planopillaris, as shown by one patient's symptom regression.
research Decision Letter: Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Role of Androgen on Physiological Function of Pilosebaceous Unit
Androgen affects oil production and hair growth in the skin.
research Hdac1 and Hdac2 Regulate the Quiescent State and Survival of Hair-Follicle Mesenchymal Niche
Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
research Deciphering the Functions of the Hair Follicle Infundibulum in Skin Physiology and Disease
The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
research Developing New Graft Holding Solutions: In Vitro Evaluation of Bioactive Molecules Identifies Vitamin B12 as Micrograft Stabilizing Substance
Vitamin B12 improves the health and growth of hair micrografts.
research A Mechanism for Topical Cutaneous Calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research Cutaneous Responses to Systemic Iron: A Potential Role for Epidermal Turnover in Mammalian Iron Excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research Defective Expression of the Gap Junction Protein Pannexin-1 Channel Contributes to the Formation of PCOS-Related Androgenetic Alopecia
Higher levels of the protein Pannexin-1 may play a role in hair loss in women with PCOS.
research The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles
Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation
Desmoglein 4 is controlled by specific proteins that affect hair growth.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Deep Hair Phenomics: Implications in Endocrinology, Development, and Aging
A new tool can analyze hair to detect changes due to hormones, genetics, and aging.