Stimulation of Hair Growth Effect by Fermented Ginsenosides Using Levilactobacillus Brevis THK-D437

    November 2024 in “ Fermentation
    Eun-Ji Yi, Trang Thi Minh Nguyen, Jeehaeng Jeong, Xiangji Jin, Qiwen Zheng, S. Y. Park, Gyeong-Seon Yi, Su-Jin Yang, Tae‐Hoo Yi
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    TLDR Fermented ginsenosides from kimchi bacteria may promote hair growth better than finasteride.
    The study examines the hair-growth-promoting effects of fermented ginsenosides produced by Levilactobacillus brevis THK-D437, isolated from kimchi. In human hair dermal papilla cells, the treatment increased proliferation by 25%, surpassing the 10% increase seen with finasteride. In C57BL/6 mice, the treatment led to visible hair growth within one week, increased hair follicle numbers, and a thicker epidermis. These results suggest that fermented ginsenosides could be a promising natural alternative for hair growth promotion and hair loss prevention, although further research is needed to understand the interactions between ginsenoside components.
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