research The Osler Lecture 2012: Pharmacology 2.0, Medicines, Drugs, and Human Enhancement
The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.
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research Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata
Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Efficacy of 5% Minoxidil Versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss
Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.
research Platelet-Rich Plasma Contains High Concentrations of DKK1, A Potent Inhibitor of Wnt Signaling That Limits Bone Regeneration and Hair Growth
Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.
research Telogen Effluvium and Minoxidil
Minoxidil treatment may cause hair loss.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Scanning Electrochemical Microscopy of Iontophoretic Transport in Hairless Mouse Skin: Analysis of the Relative Contributions of Diffusion, Migration, and Electroosmosis to Transport in Hair Follicles
Hair follicles significantly enhance electroosmotic transport during iontophoresis.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Fibrosing Alopecia in a Pattern Distribution
Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
research Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation
Low-dose oral minoxidil improved or stabilized hair loss in some patients, but higher doses may be needed for significant effects.
research Combination Tofacitinib and Oral Minoxidil Treatment for Severe Alopecia Areata
Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Pediatric Androgenetic Alopecia: A Review
Early diagnosis and treatment, like topical minoxidil, can prevent hair loss in children.
research Telogen Effluvium, Beau's Lines, and Acral Peeling Associated with COVID-19 Infection
A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.
research Alopecia as a Systemic Disease
Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
research Androgenetic Alopecia in COVID-19: Compared to What?
Hair loss link to severe COVID-19 unclear.
research Efficacy of Antihistamines in Combination with Topical Corticosteroid and Superficial Cryotherapy for Treatment of Alopecia Areata: A Retrospective Cohort Study
Adding antihistamines to topical corticosteroid and cryotherapy may improve hair regrowth in alopecia areata patients.
research Combination Oral Minoxidil and Spironolactone for the Treatment of Androgenetic Alopecia in Adolescent Girls
Minoxidil and spironolactone improve hair density and reduce shedding in girls.
research Cutaneous Manifestations of Polycystic Ovary Syndrome
Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.
research Platelet-Rich Plasma Lacks Evidence of Clinically Significant Improvement in Androgenetic Alopecia
No strong proof that platelet-rich plasma effectively treats hair loss.
research Comment on 'Androgenetic Alopecia Present in the Majority of Patients Hospitalized with COVID-19'
Hair loss link to COVID-19 severity likely due to other factors.
research Efficacy of Intradermal Platelet-Rich Plasma Injections for Androgenetic Alopecia in Men: A Before-After Study
PRP injections increased hair density in men with hair loss but didn't work for everyone and more research is needed.
research GTL1 Is Required for a Robust Root Hair Growth Response to Avoid Nutrient Overloading
GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.
research Platelet-Rich Plasma Has a Place in the Treatment of Androgenetic Alopecia
PRP helps treat hair loss effectively with natural methods.
research Response to Letter to the Editor on Inflammation in Androgenetic Alopecia
Inflammation and fibrosis are important factors in hair loss, but more research with better control samples is needed.
research 5α-Reductase Inhibitors in Men Aged 50 Years or Older with Androgenetic Alopecia: A Retrospective Study
5ARI treatment improves hair growth in older men with minimal side effects.
research Trichogram Hair and Scalp Feature Extraction and Analysis Using Image Processing
"TRICHOASSIST" is a system that analyzes hair and scalp images to help diagnose scalp diseases.
research Mandibular Trauma: From the Simple to the Complex and Everything in Between
The document concludes that understanding hair loss patterns and careful surgical techniques are key for successful hair transplantation in oral and maxillofacial surgery.
research Commensal Microbiome Promotes Hair Follicle Regeneration by Inducing Keratinocyte HIF-1α Signaling and Glutamine Metabolism
Skin bacteria help hair regrow by boosting cell metabolism.