23 citations,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
July 2018 in “Elsevier eBooks” New hair loss treatments show promise, but more research is needed to confirm their effectiveness.
69 citations,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
56 citations,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
28 citations,
March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
15 citations,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
13 citations,
March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
6 citations,
January 2023 in “npj regenerative medicine” Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
February 2024 in “Biomedical materials” Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
October 2023 in “Scientific reports” Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
October 2021 in “Research Square (Research Square)” Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.
October 2019 in “Skin appendage disorders” The vitreous membrane in hair follicles changes shape during the hair cycle and may affect hair growth and nutrient exchange.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
41 citations,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
25 citations,
July 2017 in “Journal of Stomatology, Oral and Maxillofacial Surgery” PRP injections help regrow hair, reduce hair loss, and increase hair thickness, but effects decrease without ongoing treatment.
15 citations,
May 2020 in “Journal of Dermatological Treatment” PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.
14 citations,
January 2014 in “Cells Tissues Organs” Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
13 citations,
December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
8 citations,
January 2016 in “Cells tissues organs” Norepinephrine helps skin cells grow, which is important for hair growth.
4 citations,
June 2021 in “Frontiers in Pharmacology” Bone marrow stem cells and their medium help hair regrowth.
2 citations,
May 2022 in “Stem cell research & therapy” Disrupted stem cell signals in hairpoor mice cause hair loss.
May 2023 in “Stem cell research & therapy” New method efficiently isolates hair growth cells from newborn mouse skin.