2 citations
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February 2012 in “PubMed” This study found that Gp₄G increased hair length, papilla cell numbers, and versican deposition in treated animals, potentially through alterations in hair follicle phases and nucleotide concentrations.
16 citations
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October 2018 in “BMC Complementary and Alternative Medicine” In this animal study, the methanolic extract of Crataeva nurvala leaves was found to possess sedative and anxiolytic properties, potentially linked to GABAergic activity and certain neuroactive compounds.
July 2008 in “Planta Medica” This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.
December 2020 in “한국인그리에학회지” This study found that topical application of astrigent persimmon fruit extract may promote hair growth in a Black mice model by increasing the hair existing area and hair length without significantly increasing hair follicles.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effectiveness of three formulated hair conditioners—Herbal, Synthetic, and Ayurvedic—using organoleptic and physicochemical tests like pH, Dirt Dispersion, and Stability, with the main aim to develop a product that meets user compliance and desired hair care effects.
4 citations
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October 2013 in “Botanics Targets and Therapy” In this animal study, a herbal preparation demonstrated moderate anti-inflammatory and immunomodulating properties, suggesting its potential usefulness for preventing and treating alopecia.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair oil containing Euphorbia hirta extract showed promising results for promoting hair growth in testosterone-induced alopecia in mice, suggesting it as a potential alternative to synthetic treatments.
2 citations
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October 2024 in “Phytochemistry Reviews” Abrus precatorius has medicinal benefits but can be toxic.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, Clitoria ternatea (Sangu Poo) was noted for its potential roles in health and skincare, with lab tests showing antioxidant, antimicrobial, liver-protective, and cancer-related activities; however, human trial evidence is lacking, impacting consistent quality and progress.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
3 citations
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January 2003 This study found that SPELA 707, a herbal extract mixture, enhanced hair density and promoted hair growth by converting hair into the anagen phase in individuals with androgenetic alopecia and C3H mice.
19 citations
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September 1995 in “Food and nutrition bulletin” This article reviews the toxic effects of mimosine in Leucaena leucocephala and discusses various methods to mitigate its toxicity but presents no new findings.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the potential benefits of flaxseed oil for moisturizing and nourishing hair, highlighting its rich content of beneficial compounds, but it reports no clinical results.
3 citations
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March 2019 in “Contact Dermatitis” Using Indian marking nut sap for hair loss caused a skin rash on a woman's face.
This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
25 citations
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January 2011 in “Pharmacognosy magazine” This study found that Nardostachys jatamansi DC rhizome extracts and specific isolated terpenoids promoted hair growth.
December 2010 in “대한미용학회지” This study found that Polygoni multiflori Radix water extracts stimulated hair growth and hair follicle development in mice, suggesting it may be safer than minoxidil.
October 2025 in “Jurnal Medisains Kesehatan” This experimental study found that leaf extracts from Averrhoa bilimbi and Muntingia calabura significantly inhibited the growth of Staphylococcus aureus, with M. calabura demonstrating stronger antibacterial activity, suggesting potential for acne treatment.
7 citations
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September 2024 in “Journal of Microbiology and Biotechnology” This study found that Peperomia pellucida, a plant traditionally consumed in some countries, contains various antioxidants and extends lifespan under oxidative stress in Drosophila, with no observed toxicity in mice, supporting its potential safety and use in foods and pharmaceuticals.
5 citations
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April 2022 in “Egyptian Journal of Chemistry” This study found that a subfraction from Sansevieria trifasciata showed higher hair growth activity than other fractions in tests on rabbits.
May 2025 in “International Research Journal of Ayurveda & Yoga” This pilot study found that using a topical Carica papaya latex gel for 28 days reduced hair fall and promoted hair regrowth in individuals with Indralupta, although the bald patch size did not significantly change, indicating the potential need for longer treatment or additional interventions.
27 citations
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January 2010 in “Animal” In these studies, researchers found that Peruvian camelids reach mature skin follicle development early, with specific cuticular characteristics useful for distinguishing fleece types, while Bolivian llamas have a mature follicle apparatus present at birth.
April 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.
January 2026 in “MEDS Clinical Medicine” This review discusses the combined use of plum-blossom and Daoma needle therapy for androgenic alopecia, emphasizing its potential benefits and the need for further clinical research, but reports no new results.
This review highlights the therapeutic potential of Hibiscus rosa-sinensis, detailing its significant medicinal value for treating various conditions such as wounds, infections, and diabetes, attributed primarily to its bioactive compounds like flavonoids and tannins.
January 2025 in “Current Issues in Molecular Biology” This study explored the anti-hair loss potential of plant extracts like licorice, salvia miltiorrhiza, and others, finding they increased ALP and β-catenin expression and reduced TGF-β1 and IL-6 in human dermal papilla cells without cytotoxicity.
October 2024 in “Journal of Plant Growth Regulation” Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.
October 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that supplemented Erzhi Wan enhanced hair regrowth in a mouse model of androgenetic alopecia and identified potential mechanisms through oxidative stress and signaling pathways.
17 citations
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March 2020 in “Frontiers in Chemistry” This study isolated new geranylated coumarins from Mammea siamensis flowers and found that several of these compounds inhibit testosterone 5α-reductase.
This study suggests that a candlenut oil nanoemulsion formulation could enhance hair growth activity in Sprague Dawley rats, with stability for up to 14 days at room temperature.