Hair Growth Promotion Effects of Polygoni Multiflori Radix Water Extracts in C57BL/6 Mice

    December 2010 in “ 대한미용학회지
    이경미, 이재순, 오지영, 김영철
    TLDR PMWE effectively stimulates hair growth and is safer than minoxidil.
    The study investigated the effects of Polygoni multiflori Radix water extracts (PMWE) on hair growth in C57BL/6 mice. Female mice were divided into four groups: normal (N), vehicle control (VC), positive control (PC with 3% minoxidil), and experimental (E with PMWE). Treatments were applied topically for 4 weeks. Both PMWE and minoxidil accelerated hair regrowth and promoted hair follicle development compared to N and VC groups. PMWE was found to be safer than minoxidil, as indicated by fewer significant changes in organ weights and blood parameters. The study concluded that PMWE effectively stimulated hair growth and was safer than minoxidil.
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