Antialopecia Activity and IR Spectrometry Characterization of Bioactive Compounds From Sansevieria Trifasciata

The study investigates the potential of Sansevieria trifasciata as a natural treatment for Androgenetic Alopecia (AGA), which accounts for over 90% of alopecia cases. Current AGA treatments have toxic side effects, prompting the need for safer alternatives. Researchers isolated bioactive compounds from Sansevieria trifasciata using column chromatography and assessed their hair growth activity through the modified Tanaka method on rabbits. Infrared spectroscopy (FT-IR) was used to characterize the isolates. Among the six subfractions obtained, subfraction-C demonstrated the highest hair growth activity, with a hair growth length of 2.80 cm. This suggests that Sansevieria trifasciata could be a promising natural source for developing new AGA treatments.