An In Vitro Approach: Antibacterial Activity of Sansevieria Trifasciata Prain Leaves with Chemometric Analysis

    February 2024 in “ Jurnal Sains dan Kesehatan
    Henny Kasmawati, Nurramadhani A. Sida, Arfan Arfan, Wa Ode Dian Indrayanti, Arman Rusman
    Studysummary This study examined the antibacterial activity of Sansevieria trifasciata Prain. extracts and its ethyl acetate fractions, finding that both the extract and 40% fraction significantly inhibited bacterial growth, showing potential akin to ciprofloxacin in inhibiting S. aureus, E. coli, and P. aeruginosa. Our plain-language summary of this paper — not a Tressless recommendation.
    This study evaluates the antibacterial activity of Sansevieria trifasciata Prain. leaf extracts and ethyl acetate fractions. The leaves were processed with ethanol and ethyl acetate, and their effects were compared to ciprofloxacin (positive control) and DMSO (negative control). The study found that both the extract and the 40% ethyl acetate fraction (ET40%) showed significant antibacterial activity against S. aureus, E. coli, and P. aeruginosa, with inhibition zones and percent inhibition comparable to ciprofloxacin. The chemometric analysis confirmed that the extract and ET40% had similar antibacterial effects to the positive control, indicating their potential for development as antibacterial agents.
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