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This study observed that platelet-rich plasma samples from female patients show significant variability in growth factor secretion, which may influence the inconsistent clinical response in alopecia treatment.

This study developed a multifunctional core-shell fiber dressing that preserves platelet-rich plasma for 180 days, facilitating sustained growth factor release and improved wound healing.

This article discusses the early development of hair follicles with a focus on the formation of epidermal thickenings called placodes, reporting no new experimental results.

In this study, Rosa multiflora root extracts showed strong antioxidant activity and promoted expression of growth factors IGF1 and PDGFB, suggesting potential use as a natural hair growth agent.

This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.

This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.

This study reported that micro-needling with Low-Level LED Therapy and Growth Factors may improve hair density in mild-to-moderate hair loss and telogen effluvium related to COVID-19, based on preliminary observations.

This review summarizes major growth factors that promote hair follicle growth, but it reports no new experimental findings.

In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.

In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.

This article discusses the concept of telogen effluvium, introduced in 1961, characterized by diffuse scalp hair loss due to various triggers, and reports no new clinical findings.

In this study, miliacin combined with polar lipids significantly stimulated IGF1 production, increased the renewal of keratinocytes, and enhanced collagen thickness in a hair follicle model.

In this study, certain cytokines and growth factors were found to significantly regulate hair growth in vitro, with EGF, TNFα, and IL-1β particularly inhibiting it.

This study investigated different centrifugation systems and found that low-speed protocols and certified centrifuges produced better-quality platelet-rich fibrin and recommended using FDA-approved glass tubes for safe and effective regenerative outcomes.

This study found that the FGF-2 mimetic SUN11602 and VEGF mimetic ONO-1301 had unique effects on skin fibroblasts and keratinocytes, indicating potential for improving wound healing.

The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.

This study found PRP treatment significantly increased hair count and anagen hairs in male patients with androgenetic alopecia, but there was no correlation between therapeutic response and platelet or growth factor levels.

This study found that prolactin can induce premature catagen in both mouse and human hair follicles and suggests that targeting prolactin and TGF-β receptors may be promising for treating androgenetic alopecia.

This study found that treating SM-MSCs with 150 μg/mL IGF-1 led to the highest increases in growth factor proteins BMP-2, FGF-18, and TGF-β1 in their conditioned media.

This article reviews various aspects of growth factor research, highlighting their role in treatments and emphasizing the need for further clinical trials to validate their efficacy in biomedical applications.

In this study, FGF12 was found to promote hair growth in mice by inducing the anagen phase of hair follicles, suggesting potential for hair loss therapy.

In three patients with diabetic ulcers, this study reported remarkable wound healing and tissue regeneration after 3 to 6 weekly applications of growth factors-rich plasma and membrane treatment.

This study found that iontophoresis combined with growth factors improved hair density and reduced hair loss in patients with androgenetic alopecia and telogen effluvium, with no serious side effects reported.

This review discusses mesenchymal stem cells' role in tissue regeneration and skin anti-aging, highlighting their migration to damaged sites and secretome effects, but reports no new clinical results.

In this study, researchers found that the variability in growth factor expression, particularly TGFβ1, in PRP samples could influence patient responses to hair loss treatment with PRP therapy.

This study evaluated a multimodal treatment involving iontophoresis-assisted growth factor delivery for hair loss, reporting significant reductions in daily hair shedding and high patient satisfaction, particularly in those with telogen effluvium; however, the design suggests these findings should be seen as preliminary.

This commentary suggests that shifting from inconsistent autologous PRP to more standardized PRP-inspired formulations could improve treatment consistency for alopecia, emphasizing the need for careful characterization and clinical studies to validate safety and efficacy.

This study found that autologous growth factor injections for androgenetic alopecia improved hair density, thickness, and patient satisfaction over 12 months; however, high bias risk and non-standardized methods limit the evidence's reliability, highlighting the need for larger, standardized trials.

This study concluded that Growth Factor Concentrate was more effective than Platelet-Rich Plasma in enhancing hair growth and patient satisfaction for individuals with androgenic alopecia and telogen effluvium, while maintaining similar safety.

This study found that supercritical fluid extraction of germinated perilla seed significantly promoted hair follicle cell proliferation and gene expression related to hair growth, suggesting its potential as a natural treatment for hair loss.