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SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Fat cells in the skin help start healing and form important repair cells after injury.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Cell aging can be both good and bad for tissue repair.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.

Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Finasteride and minoxidil work best together for hair loss.

Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Type I interferons play a key role in the development of various skin diseases.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.