35 citations,
August 2009 in “Journal of the American Academy of Dermatology” Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.
January 2023 in “Food and nutrition sciences” Most people using the supplement Renew saw health improvements, especially in sleep and energy, faster than with regular vitamins.
37 citations,
January 2010 in “Internal Medicine” A woman's liver was damaged by taking the herbal supplement Shou-Wu-Pian, but it got better after she stopped using it.
2 citations,
January 2018 in “Elsevier eBooks” Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
62 citations,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
17 citations,
June 2012 in “The Anatolian journal of cardiology” Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.
3 citations,
June 2017 in “Medical lasers” A treatment combining laser energy and injections improved hair loss and unexpectedly also reduced hair graying.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
1 citations,
February 2021 in “International Journal of Research in Dermatology” Premature graying of hair significantly harms psychological and social wellbeing.
1 citations,
September 2019 in “Journal of cosmetic dermatology” Lead and selenium levels don't cause premature graying.
105 citations,
April 2005 in “Cell” Hair graying happens because certain cells aren't maintained properly.
46 citations,
December 2014 in “Journal of The American Academy of Dermatology” Premature hair graying in young men is linked to family history, obesity, and smoking.
33 citations,
January 2004 in “Photochemistry and Photobiology” Superoxide dismutase (SOD) can prevent hair graying in mice.
26 citations,
January 2018 in “Annals of dermatology/Annals of Dermatology” Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
20 citations,
January 2016 in “International journal of trichology” Young Indians with premature graying often have lower levels of certain nutrients and unhealthy lifestyles.
13 citations,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
12 citations,
May 2019 in “Journal of cosmetic dermatology” Effective treatments for premature hair graying still require significant research.
12 citations,
November 2004 in “Photochemistry and Photobiology” Superoxide dismutase (SOD) can prevent hair graying in mice.
7 citations,
December 2013 in “The Journal of Dermatology” A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.
5 citations,
February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
4 citations,
January 2016 in “Annals of dermatology/Annals of Dermatology” Iron supplements can restore normal hair color in cases of premature graying linked to iron deficiency.
2 citations,
November 2017 in “Cardiovascular endocrinology” Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.
1 citations,
November 2022 in “International journal of trichology” A woman's premature gray hair turned mostly black again after using Greyverse solution and hair supplements for 5 months.
1 citations,
October 2020 in “Journal of Cosmetic Dermatology” Low iron levels are linked to premature graying of hair, but vitamin D levels are not.
1 citations,
December 2017 in “The Medical journal of Basrah University” People with metabolic syndrome get gray hair earlier.
1 citations,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
Good nutrition may help prevent premature hair graying.
Premature graying of hair is linked to vitamin D and B12 deficiencies, thyroid issues, iron imbalance, stress, and lifestyle habits, and affects quality of life.
January 2024 in “Grail of science” Premature hair graying is caused by various factors and mechanisms.