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    Glossary GPR44

    protein receptor involved in immune response and inflammation

    GPR44, also known as CRTH2 or the DP2 receptor, is a type of protein found on the surface of certain cells that plays a role in the body's immune response. It is involved in the process of inflammation and allergic reactions by binding to prostaglandin D2, a molecule that can cause symptoms like itching, swelling, and redness. This receptor is also being studied for its potential role in conditions like asthma and alopecia, where it may influence hair growth and immune system activity.

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    1. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44 Journal of Investigative Dermatology · 2012 · 68 citations
    2. Prostaglandin D2(PGD2); prostaglandin D2 receptor (CRTH2; GPR44; CD294); prostaglandin D2 synthase (PTGDS) Science-business Exchange · 2012 · 2 citations
    3. Gpr54 deletion accelerates hair cycle and hair regeneration EMBO Reports · 2024 · 1 citations
    4. The effects of GPR40 agonists on hair growth are mediated by ANGPTL4 Biomedicine & Pharmacotherapy · 2023
    5. Prostaglandin D <sub>2</sub> Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012 · 205 citations
    6. Does prostaglandin D<sub>2</sub> hold the cure to male pattern baldness? Experimental Dermatology · 2014 · 57 citations
    7. 男性型脱毛症の原因についての手がかり Nature digest · 2012
    8. News updates Lab Animal · 2012
    9. Topical Prostaglandin Analogues in Androgenetic Alopecia: A Systematic Review of Clinical Evidence International Journal of Drug Delivery Technology · 2026
    10. Epidemiologic Study of Gene Distribution in Romanian and Brazilian Patients with Non-Cicatricial Alopecia Medicina-lithuania · 2023
    11. Investigations of 13 Genes in Non-Cicatricial Alopecia 2023
    12. Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2016
    13. Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    14. Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    15. The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome BMC Genomics · 2022 · 17 citations
    16. Physiology of Male Gonadotropic Axis and Disorders of Sex Development Springer eBooks · 2017
    17. Novel lysophosphoplipid receptors: their structure and function Journal of Lipid Research · 2014 · 158 citations
    18. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds Nature Communications · 2019 · 301 citations
    19. Stem cell dynamics, migration and plasticity during wound healing Nature Cell Biology · 2018 · 211 citations
    20. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    21. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration Cell Stem Cell · 2015 · 128 citations
    22. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair Cell Stem Cell · 2020 · 124 citations
    23. Hyaluronidase Modulates Inflammatory Response and Accelerates the Cutaneous Wound Healing PLoS ONE · 2014 · 98 citations
    24. Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review International Journal of Women's Dermatology · 2018 · 66 citations
    25. Bacteria induce skin regeneration via IL-1β signaling Cell Host & Microbe · 2021 · 53 citations
    26. Mechanism of action of herbs and their active constituents used in hair loss treatment Fitoterapia · 2016 · 47 citations
    27. Emerging treatments in alopecia Expert Opinion on Emerging Drugs · 2014 · 47 citations
    28. Reflections on how wound healing-promoting effects of the hair follicle can be translated into clinical practice Experimental Dermatology · 2014 · 43 citations
    29. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia Archives of Dermatological Research · 2018 · 39 citations
    30. The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics International Journal of Molecular Sciences · 2019 · 38 citations