303 citations
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October 2000 in “Nature” This study found that RXRα plays a critical role in hair cycling and keratinocyte functions in mice, likely through its interaction with VDR in epidermal cells.
133 citations
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January 2009 in “Nature” This study identified gene expression patterns in a mouse model that may influence tumor susceptibility and tissue functions related to inflammation and cell proliferation, highlighting Lgr5 and the vitamin D receptor as key regulators.
13 citations
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March 1962 in “Nature” This study found that zinc content decreases not only in the blood but also in other tissues like the heart, spleen, liver, and kidney of carcinoma patients.
1 citations
,
July 1935 in “Nature” This study found super-contraction in the guard hairs of fur-bearing animals, likely due to oxidation in living animals, primarily affecting white and red foxes without prior heat or chemical treatment.
425 citations
,
June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
231 citations
,
October 1999 in “Journal of Clinical Investigation” This study found that administering an adenovirus vector to increase Sonic hedgehog gene expression in mouse skin accelerated the transition of hair follicles into the growth phase, promoting hair growth.
86 citations
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August 2021 in “Polymers” This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.
24 citations
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November 2023 in “Nature” In this study, researchers demonstrated that the expression of the oncogene SmoM2 leads to basal cell carcinoma in the ear epidermis of mice but not in the back skin, with differences in susceptibility linked to the composition of the extracellular matrix.
20 citations
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July 2019 in “Stem cell investigation” This study found that the combination of stromal vascular fraction and platelet-rich plasma accelerated wound healing in rats more effectively than either treatment alone or saline.
15 citations
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July 2020 in “AAPS PharmSciTech” 12 citations
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January 2023 in “AAPS PharmSciTech” 12 citations
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January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This systematic review describes current findings on the use of recombinant epidermal growth factor (rhEGF) for skin aging and wound healing, emphasizing its potential benefits but highlighting the need for more controlled studies to optimize dosing and treatment protocols.
9 citations
,
January 2023 in “Indian Dermatology Online Journal” This review discusses the use of aesthetic treatments for medical purposes and their therapeutic potential but provides no new clinical results.
6 citations
,
September 2020 in “Frontiers in Neurology” This study reported that the coexistence of myasthenia gravis and primary Sjögren's syndrome is rare, and managing the progress of myasthenia gravis is crucial for treatment, while it does not adversely impact Sjögren's syndrome.
5 citations
,
July 2013 in “InTech eBooks” This book reviews the role of skin biopsy in diagnosing and treating various dermatological diseases, discussing site selection and applications for conditions like alopecia and pemphigus, but reports no new clinical results.
2 citations
,
May 2021 in “IOP Conference Series Earth and Environmental Science” This study found that treating SM-MSCs with 150 μg/mL IGF-1 led to the highest increases in growth factor proteins BMP-2, FGF-18, and TGF-β1 in their conditioned media.
2 citations
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September 2022 in “Cytotherapy” This review summarizes recent research on the therapeutic uses of adipose-derived stem cells for wound healing and treating skin diseases but does not provide new experimental results.
2 citations
,
January 2021 2 citations
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January 2017 Hair movement can indicate hair quality and health.
1 citations
,
April 2023 in “Preprints.org” This study found that the guided SEFFI technique for facial volume restoration and anti-aging is minimally invasive with a low complication rate, suggesting it as a promising treatment option.
The study found that the combined administration of regulatory T cells and rapamycin improved outcomes in an experimental model of chronic graft-versus-host disease.
June 2026 in “Molecular Biology Reports”
May 2026 in “Applied Biochemistry and Biotechnology” Lemon-derived vesicles may help hair grow.
This review reports that exosome-based therapies, coupled with nanotechnology and AI, show promise in aesthetic medicine, notably in skin rejuvenation and hair restoration, but large-scale trials and clearer regulatory frameworks are needed for effective clinical adoption.
August 2024 in “Indian Journal of Skin Allergy” This review outlines the current state of stem cell therapy in dermatology, highlighting its potential for treating a variety of skin disorders and conditions, while emphasizing the need for further controlled studies to standardize treatment and fully understand its efficacy and limitations.
April 2024 in “JCT research” Hair movement can indicate hair quality and health.
February 2024 in “Drug Delivery and Translational Research” In this study, a newly developed cardamonin-loaded liposomal formulation significantly enhanced hair growth and improved hair follicle performance in mice with androgenic alopecia.
148 citations
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August 2022 in “Stem Cell Research & Therapy” This study found that encapsulating hADSCs-derived exosomes in PF-127 hydrogel improved wound healing in mice, suggesting a promising approach for enhancing skin repair.
119 citations
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December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.