Myasthenia Gravis Coexisting With Primary Sjögren's Syndrome: Report of Three Cases and Literature Review

The document reported on the rare coexistence of Myasthenia Gravis (MG) and Primary Sjögren's Syndrome (pSS) through three case studies and a literature review of 17 cases. It found a female predominance and a median onset age of 48 years, with MG often occurring before pSS diagnosis. Most patients exhibited generalized MG, and anti-acetylcholine receptor antibodies were positive in 12 out of 17 cases. Treatment commonly involved cholinesterase inhibitors, and most patients showed improvement, although one patient died from an MG crisis. The study highlighted the importance of recognizing this rare coexistence for appropriate management and called for larger multicenter studies to better understand this co-morbidity.