Myasthenia Gravis Coexisting With Primary Sjögren's Syndrome: Report of Three Cases and Literature Review

This study reported on the rare coexistence of myasthenia gravis (MG) and primary Sjögren's syndrome (pSS) through three cases and a review of 17 patients. The majority of patients were female, with a median age of 48 years. MG symptoms included fatigable ptosis, bulbar symptoms, muscle fatigability, and diplopia, while pSS symptoms included sicca symptoms, swollen exocrine glands, and joint pain. Anti-acetylcholine receptor antibodies were positive in 70.6% of patients. Treatments included cholinesterase inhibitors, thymectomy, steroids, and immunosuppressants, with most patients showing improvement. The study concluded that while the coexistence of MG and pSS is rare, managing MG is crucial as it does not negatively impact the course of pSS.