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This study examined a case of postmenopausal virilization in a woman and found that despite normal imaging, bilateral salpingo-oophorectomy revealed rare ovarian Leydig cell and Brenner tumors as the source of hyperandrogenism, with symptoms resolving post-surgery.

This case report describes a woman with virilization syndrome who experienced a reduction in androgen levels and reversal of alopecia after removal of a Leydig cell tumor from her ovary.

This case report suggests that ovarian steroid cell tumors should be considered in postmenopausal women with hirsutism and elevated testosterone, with surgery being effective in resolving symptoms and preventing recurrence.

This case report illustrates a rare instance of mixed germ cell tumor in the pituitary with hyperandrogenism, emphasizing the importance of thorough examination and hormone evaluation in identifying hormonal dysfunctions.

In this case report, the authors describe the diagnosis and management of a rare case of hyperandrogenism in a postmenopausal woman, attributed to coexisting ovarian Leydig cell and Brenner tumors, with improvement in symptoms following bilateral salpingo-oophorectomy.

This case study found that a 1.6cm ovarian Leydig cell tumor, causing hyperandrogenism in a postmenopausal woman, evaded detection on standard imaging techniques, underscoring the difficulty of diagnosing such tumors with imaging alone.

An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.

In this case report, an embryonal cell carcinoma of the testicle was associated with polycythemia and markedly elevated hormone levels without secondary sexual characteristics, which were restored after treatment.

This case report describes a postmenopausal woman with virilization and an ovarian steroid cell tumor, highlighting the rarity and diagnostic importance of such tumors in this demographic.

This case report describes a 72-year-old woman with a steroid cell tumor of the ovary, highlighting the critical role of imaging, biochemical evaluation, and pathology in diagnosing and managing hormonally active ovarian tumors that cause virilization in postmenopausal women.

This report presents a case of functioning adrenocortical oncocytoma in a 9-year-old girl with virilization symptoms, successfully treated with laparoscopic surgery.

This case report presents a rare instance of an ovarian steroid cell tumor in a 68-year-old female with virilism, which normalized androgen levels following surgical removal.

In this case report, a 68-year-old woman with a Leydig cell tumor of the ovary experienced virilization, and surgical removal led to normalization of testosterone levels and regression of symptoms.

This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.

In this case report, the researchers described a postmenopausal woman with androgenic symptoms who was found to have a benign Leydig cell tumor of the left ovary, indicated by elevated testosterone levels and MRI findings, which was successfully treated with surgery.

This case report describes an extremely rare instance of seminoma in an adult with SRY-negative 46,XX testicular disorder of sex development, uniquely presenting as acute abdomen due to gonadal torsion.

This case study reported two instances of female androgenetic alopecia with male pattern reversed after surgical removal of an ovarian tumor.

In this case report, a 62-year-old woman with hyperandrogenism and polycythemia was diagnosed with a rare ovarian steroid cell tumor, highlighting the importance of considering such tumors in similar presentations; surgical removal led to symptom and lab normalization.

This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.

This case report describes a trichoblastoma in a 58-year-old man's leg, which was successfully excised without recurrence observed after 9 months.

This case report describes a 69-year-old woman with hirsutism and elevated serum testosterone, where surgery resolved symptoms and serum testosterone, suggesting ovarian steroid cell tumor consideration in similar profiles.

This clinical case study reports on a postmenopausal woman experiencing hair loss and virilization symptoms, which were ultimately attributed to rare ovarian tumors identified after a bilateral salpingo-oophorectomy, despite normal imaging results.

This case report details a postmenopausal woman with hyperandrogenism due to both adrenal adenoma and ovarian hyperthecosis, highlighting the effectiveness of hormonal suppression and venous sampling for diagnosis.

This case study reported that sudden hyperandrogenism in postmenopausal women may indicate hormonally active ovarian tumors such as Leydig cell tumors, which can be effectively treated with surgery.

This case report illustrates that Leydig cell tumors, despite causing significantly elevated androgen levels, can be difficult to localize due to their small size, as demonstrated in a 42-year-old woman whose tumor was only identified after oophorectomy.

This case report from a German study detailed a 2-year-old girl with virilization and precocious puberty due to a rare ovarian steroid cell tumor, finding that post-surgery, her elevated hormone levels normalized within a week, and ongoing follow-up showed no need for chemotherapy.

This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.

This report describes a rare case of a malignant feminizing adrenocortical tumor in a 44-year-old man who lacked the typical presentation of gynecomastia and died four months after diagnosis despite treatment.

This case report details a 73-year-old woman with significant hirsutism and hair loss linked to a rare ovarian Leydig cell tumor, which was resolved by bilateral salpingo-oophorectomy, normalizing her testosterone levels and addressing her symptoms.

In this case study, a 68-year-old woman with hyperandrogenism and presumed ovarian origin responded well to GnRH agonist therapy, normalizing testosterone levels and stabilizing blood pressure, suggesting its effectiveness as a non-surgical treatment option.